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PMID: 14381429 Published · ppublish English Journal Article

The fine structure of neurons.

The Journal of biophysical and biochemical cytology ·Vol. 1 ·No. 1 ·1955-01-00 ·Pages 69-88

PALAY SL, PALADE GE

Abstract

1. Thin sections of representative neurons from intramural, sympathetic and dorsal root ganglia, medulla oblongata, and cerebellar cortex were studied with the aid of the electron microscope. 2. The Nissl substance of these neurons consists of masses of endoplasmic reticulum showing various degrees of orientation; upon and between the cisternae, tubules, and vesicles of the reticulum lie clusters of punctate granules, 10 to 30 mmicro in diameter. 3. A second system of membranes can be distinguished from the endoplasmic reticulum of the Nissl bodies by shallower and more tightly packed cisternae and by absence of granules. Intermediate forms between the two membranous systems have been found. 4. The cytoplasm between Nissl bodies contains numerous mitochondria, rounded lipid inclusions, and fine filaments.

Keywords
MICROSCOPY ELECTRON NEURONS
MeSH Terms
Animals Cytoplasm Cytoplasmic Granules Electrons Endoplasmic Reticulum Ganglia, Spinal Microscopy Microscopy, Electron Mitochondria Neurons Nissl Bodies
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
PALAY S L
PALADE G E
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31 references, click to expand
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Article Info
Journal
The Journal of biophysical and biochemical cytology
Abbr.
J Biophys Biochem Cytol
ISSN
0095-9901
DOI
10.1083/jcb.1.1.69
Published
1955-01-00
Pages
69-88
Language
English
Region
United States
NLM ID
17840020R
PMCID
PMC2223597
Subset
OM
External Links
PubMed source DOI: 10.1083/jcb.1.1.69 PMC Full Text
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