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PMID: 1443658 Published · ppublish English Journal Article

Local signalling in dermomyotomal cell type specification.

Anatomy and embryology ·Vol. 186 ·No. 5 ·1992-10-00 ·Pages 505-10

Christ B, Brand-Saberi B, Grim M, Wilting J

Abstract

The development and differentiation of the avian myotome was studied after removal of the neural tube, including neural crest, and after replacement of dorsal half-somites by ventral half-somites. Results show that in the absence of neural tissue myoblast differentiation within the somites does not take place. Ventral half-somites are able to undergo muscle differentiation if they were grafted in place of dorsal half somites. It is suggested that local signals must be responsible for the dorsalisation of the newly formed somite including myoblast differentiation. Neural crest cells are discussed as possible sources of these signals.

MeSH Terms
Animals Cell Differentiation Chick Embryo Coturnix/embryology Extremities/embryology Immunoenzyme Techniques Muscles/cytology,embryology Neural Crest/cytology,embryology
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Christ B
Anatomisches Institut, Albert-Ludwigs-Universität Freiburg, Federal Republic of Germany.
Brand-Saberi B
Grim M
Wilting J
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Article Info
Journal
Anatomy and embryology
Abbr.
Anat Embryol (Berl)
ISSN
0340-2061
Published
1992-10-00
Pages
505-10
Language
English
Region
Germany
NLM ID
7505194
Subset
IM
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