The preparation and some properties of penicillenic acid derivatives relevant to penicillin hypersensitivity.

The Journal of experimental medicine ·Vol. 115 ·1962-04-01 ·Pages 803-19

PARKER CW, DEWECK AL, KERN M, EISEN HN

Abstract

A number of penicillenate and penicilloyl derivatives potentially useful in the study of penicillin hypersensitivity have been prepared and some of their properties described.

Keywords

ALLERGY PENICILLIN/toxicology

MeSH Terms

Hypersensitivity Penicillins/toxicity

Chemicals

Penicillins

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

PARKER C W

DEWECK A L

KERN M

EISEN H N

References (9)

9 references, click to expand

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Immediate reactions in the skin of experimental animals provoked by antibody-antigen interaction.
Prog Allergy. 1958;5:459-508 PMID: 13579002
Specific inhibition of wheal-and-erythema responses with univalent haptens and univalent antibody fragments.
J Exp Med. 1960 Dec 1;112:1211-26 PMID: 13698149
Some immunochemical properties of penicillenic acid. An antigenic determinant derived from penicillin.
J Exp Med. 1960 Dec 1;112:1227-47 PMID: 13720937
Studies on the formation of the penicillin antigen. II. Some reactions of D-benzylpenicillenic acid in aqueous solution at pH 7.5.
Arch Biochem Biophys. 1961 Apr;93:50-5 PMID: 13761468
Studies on the mechanism of the formation of the penicillin antigen. I. Delayed allergic cross-reactions among penicillin G and its degradation products.
J Exp Med. 1960 Dec 1;112:1131-56 PMID: 13761469
Studies on the mechanism of the formation of the penicillin antigen. III. The N-(D-alpha-benzylpenicilloyl) group as an antigenic determinant responsible for hypersensitivity to penicillin G.
J Exp Med. 1961 Dec 1;114:875-904 PMID: 14464604
Polyfunctional dinitrophenyl haptens as reagents for elicitation of immediate type allergic skin responses.
J Exp Med. 1962 Apr 1;115:789-801 PMID: 14483915
Hypersensitivity to penicillenic acid derivatives in human beings with penicillin allergy.
J Exp Med. 1962 Apr 1;115:821-38 PMID: 14483916

Article Info

Journal

The Journal of experimental medicine

Abbr.

J Exp Med

ISSN

0022-1007

DOI

10.1084/jem.115.4.803

Published

1962-04-01

Pages

803-19

Language

English

Region

United States

NLM ID

2985109R

PMCID

PMC2137523

Subset

External Links

PubMed source DOI: 10.1084/jem.115.4.803 PMC Full Text View journal details

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The preparation and some properties of penicillenic acid derivatives relevant to penicillin hypersensitivity.

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