Genomics. Microarrays--guilt by association.

Science (New York, N.Y.) ·Vol. 302 ·No. 5643 ·2003-10-10 ·Pages 240-1

Quackenbush J

Abstract

DNA microarray analysis has provided a wealth of data on global patterns of gene expression but has yet to deliver on its early promise of identifying networks of interacting gene products. In his Perspective, Quackenbush discusses new work (Stuart et al.) that uses evolutionary conservation of gene expression patterns in yeast, worm, fruit fly, and human in an attempt to identify functionally related groups of genes.

MeSH Terms

Animals Caenorhabditis elegans/genetics Cell Cycle/genetics Cell Division/genetics Computational Biology Drosophila melanogaster/genetics Gene Expression Gene Expression Profiling Gene Expression Regulation Genes, Fungal Genes, Helminth Genes, Insect Humans Oligonucleotide Array Sequence Analysis RNA Splicing Saccharomyces cerevisiae/genetics Species Specificity

Authors & Affiliations

1 authors, click to expand affiliations / ORCID

Quackenbush John

The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA. [email protected]

Article Info

Journal

Science (New York, N.Y.)

Abbr.

Science

ISSN

1095-9203

DOI

10.1126/science.1090887

[email protected]

Published

2003-10-10

Pages

240-1

Language

English

Region

United States

NLM ID

0404511

Subset

Corrections

CommentOn

PMID: 12934013

External Links

PubMed source DOI: 10.1126/science.1090887 View journal details

Analysis Services

Genomics. Microarrays--guilt by association.

Contact

WeChat Official Account