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PMID: 14615596 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Ethylene regulates arabidopsis development via the modulation of DELLA protein growth repressor function.

The Plant cell ·Vol. 15 ·No. 12 ·2003-12-00 ·Pages 2816-25

Achard P, Vriezen WH, Van Der Straeten D, Harberd NP

Abstract

Phytohormones regulate plant development via a poorly understood signal response network. Here, we show that the phytohormone ethylene regulates plant development at least in part via alteration of the properties of DELLA protein nuclear growth repressors, a family of proteins first identified as gibberellin (GA) signaling components. This conclusion is based on the following experimental observations. First, ethylene inhibited Arabidopsis root growth in a DELLA-dependent manner. Second, ethylene delayed the GA-induced disappearance of the DELLA protein repressor of ga1-3 from root cell nuclei via a constitutive triple response-dependent signaling pathway. Third, the ethylene-promoted "apical hook" structure of etiolated seedling hypocotyls was dependent on the relief of DELLA-mediated growth restraint. Ethylene, auxin, and GA responses now can be attributed to effects on DELLA function, suggesting that DELLA plays a key integrative role in the phytohormone signal response network.

MeSH Terms
Arabidopsis/drug effects,genetics,growth & development Arabidopsis Proteins/genetics,metabolism Ethylenes/pharmacology Germination/physiology Gibberellins/pharmacology Green Fluorescent Proteins Indoleacetic Acids/pharmacology Luminescent Proteins/genetics,metabolism Multigene Family Plant Growth Regulators/pharmacology Plant Proteins Plant Roots/drug effects,genetics,growth & development Protein Kinases/genetics,metabolism Recombinant Fusion Proteins/genetics,metabolism Seeds/physiology Signal Transduction/drug effects,genetics,physiology Transcription Factors/genetics,metabolism
Chemicals
Arabidopsis Proteins Ethylenes GAI protein, Arabidopsis Gibberellins Indoleacetic Acids Luminescent Proteins Plant Growth Regulators Plant Proteins RGL1 protein, Arabidopsis RGL2 protein, Arabidopsis Recombinant Fusion Proteins Transcription Factors Green Fluorescent Proteins ethylene Protein Kinases CTR1 protein, Arabidopsis
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Achard Patrick
John Innes Centre, Norwich NR4 7UH, United Kingdom.
Vriezen Wim H
Van Der Straeten Dominique
Harberd Nicholas P
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33 references, click to expand
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Article Info
Journal
The Plant cell
Abbr.
Plant Cell
ISSN
1040-4651
DOI
10.1105/tpc.015685
Published
2003-12-00
Epub
2003-00-13
Pages
2816-25
Language
English
Region
England
NLM ID
9208688
PMCID
PMC282807
Subset
IM
Grants
Biotechnology and Biological Sciences Research Council · BBS/E/J/00000583 · United Kingdom
External Links
PubMed source DOI: 10.1105/tpc.015685 PMC Full Text View journal details
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