Retinoids and carotenoids as inhibitors of carcinogenesis and inducers of cell-cell communication.

Nutrition reviews ·Vol. 50 ·No. 9 ·1992-09-00 ·Pages 270-4

Wolf G

Abstract

In cell cultures of carcinogen-initiated fibroblasts, a number of retinoids and carotenoids can reversibly inhibit progression to the transformed state. The anticarcinogenic action of retinoids and carotenoids is closely correlated with enhanced gap-junction cell-to-cell communication and with increased synthesis of the gap-junction protein, connexin.

MeSH Terms

Animals Anticarcinogenic Agents/pharmacology Carotenoids/pharmacology Cell Communication/drug effects Cell Transformation, Neoplastic/drug effects Humans Retinoids/pharmacology

Chemicals

Anticarcinogenic Agents Retinoids Carotenoids

Authors & Affiliations

1 authors, click to expand affiliations / ORCID

Wolf G

Department of Nutritional Sciences, University of California, Berkeley 94720.

Article Info

Journal

Nutrition reviews

Abbr.

Nutr Rev

ISSN

0029-6643

DOI

10.1111/j.1753-4887.1992.tb01345.x

Published

1992-09-00

Pages

270-4

Language

English

Region

United States

NLM ID

0376405

Subset

External Links

PubMed source DOI: 10.1111/j.1753-4887.1992.tb01345.x View journal details

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Retinoids and carotenoids as inhibitors of carcinogenesis and inducers of cell-cell communication.

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