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PMID: 14767588 Published · ppublish English Comment Editorial

Linezolid in VAP by MRSA: a better choice?

Intensive care medicine ·Vol. 30 ·No. 3 ·2004-03-00 ·Pages 343-6

Ioanas M, Lode H

Abstract

暂无摘要

MeSH Terms
Acetamides/pharmacology,therapeutic use Anti-Infective Agents/therapeutic use Cross Infection/drug therapy,etiology Humans Linezolid Methicillin Resistance/physiology Oxazolidinones/pharmacology,therapeutic use Pneumonia, Staphylococcal/drug therapy,etiology Respiration, Artificial/adverse effects Vancomycin/pharmacology,therapeutic use
Chemicals
Acetamides Anti-Infective Agents Oxazolidinones Vancomycin Linezolid
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Ioanas Malina
Lode Hartmut
References (32)
32 references, click to expand
  1. Treatment of gram-positive nosocomial pneumonia. Prospective randomized comparison of quinupristin/dalfopristin versus vancomycin. Nosocomial Pneumonia Group.
    Am J Respir Crit Care Med. 2000 Mar;161(3 Pt 1):753-62 PMID: 10712318
  2. Clinical cure and survival in Gram-positive ventilator-associated pneumonia: retrospective analysis of two double-blind studies comparing linezolid with vancomycin.
    Intensive Care Med. 2004 Mar;30(3):388-94 PMID: 14714107
  3. Inadequate antimicrobial treatment of infections: a risk factor for hospital mortality among critically ill patients.
    Chest. 1999 Feb;115(2):462-74 PMID: 10027448
  4. Ventilator-associated pneumonia.
    Am J Respir Crit Care Med. 2002 Apr 1;165(7):867-903 PMID: 11934711
  5. The activity of vancomycin against heterogeneous vancomycin-intermediate methicillin-resistant Staphylococcus aureus explored using an in vitro pharmacokinetic model.
    J Antimicrob Chemother. 2001 Nov;48(5):727-30 PMID: 11679564
  6. Linezolid vs vancomycin: analysis of two double-blind studies of patients with methicillin-resistant Staphylococcus aureus nosocomial pneumonia.
    Chest. 2003 Nov;124(5):1789-97 PMID: 14605050
  7. The prevalence of nosocomial infection in intensive care units in Europe. Results of the European Prevalence of Infection in Intensive Care (EPIC) Study. EPIC International Advisory Committee.
    JAMA. 1995 Aug 23-30;274(8):639-44 PMID: 7637145
  8. Linezolid (PNU-100766) versus vancomycin in the treatment of hospitalized patients with nosocomial pneumonia: a randomized, double-blind, multicenter study.
    Clin Infect Dis. 2001 Feb 1;32(3):402-12 PMID: 11170948
  9. Vancomycin in surgical infections due to methicillin-resistant Staphylococcus aureus with heterogeneous resistance to vancomycin.
    Lancet. 1999 May 8;353(9164):1587-8 PMID: 10334262
  10. Impact of appropriateness of initial antibiotic therapy on the outcome of ventilator-associated pneumonia.
    Intensive Care Med. 2001 Feb;27(2):355-62 PMID: 11396279
  11. Dissemination in Japanese hospitals of strains of Staphylococcus aureus heterogeneously resistant to vancomycin.
    Lancet. 1997 Dec 6;350(9092):1670-3 PMID: 9400512
  12. The prevalence and mechanisms of vancomycin resistance in Staphylococcus aureus.
    Annu Rev Microbiol. 2002;56:657-75 PMID: 12142482
  13. Vancomycin-resistant Staphylococcus aureus: no apocalypse now.
    Clin Microbiol Infect. 2003 Aug;9(8):761-5 PMID: 14616695
  14. Linezolid versus vancomycin for the treatment of methicillin-resistant Staphylococcus aureus infections.
    Clin Infect Dis. 2002 Jun 1;34(11):1481-90 PMID: 12015695
  15. Contribution of a thickened cell wall and its glutamine nonamidated component to the vancomycin resistance expressed by Staphylococcus aureus Mu50.
    Antimicrob Agents Chemother. 2000 Sep;44(9):2276-85 PMID: 10952568
  16. Ventilator-associated pneumonia by Staphylococcus aureus. Comparison of methicillin-resistant and methicillin-sensitive episodes.
    Am J Respir Crit Care Med. 1994 Dec;150(6 Pt 1):1545-9 PMID: 7952612
  17. Resistance to quinupristin-dalfopristin due to mutation of L22 ribosomal protein in Staphylococcus aureus.
    Antimicrob Agents Chemother. 2002 Jul;46(7):2200-7 PMID: 12069975
  18. Linezolid resistance in clinical isolates of Staphylococcus aureus.
    J Antimicrob Chemother. 2003 Jan;51(1):186-8 PMID: 12493812
  19. Predominant pathogens found in the European Prevalence of Infection in Intensive Care Study.
    Eur J Clin Microbiol Infect Dis. 1996 Apr;15(4):281-5 PMID: 8781877
  20. Is methicillin-resistant Staphylococcus aureus more virulent than methicillin-susceptible S. aureus? A comparative cohort study of British patients with nosocomial infection and bacteremia.
    Clin Infect Dis. 2003 Dec 1;37(11):1453-60 PMID: 14614667
  21. Penetration of vancomycin into human lung tissue.
    J Antimicrob Chemother. 1996 Nov;38(5):865-9 PMID: 8961057
  22. Impact of a rotating empiric antibiotic schedule on infectious mortality in an intensive care unit.
    Crit Care Med. 2001 Jun;29(6):1101-8 PMID: 11395583
  23. Comparison of mortality associated with methicillin-resistant and methicillin-susceptible Staphylococcus aureus bacteremia: a meta-analysis.
    Clin Infect Dis. 2003 Jan 1;36(1):53-9 PMID: 12491202
  24. Continuous versus intermittent infusion of vancomycin in severe Staphylococcal infections: prospective multicenter randomized study.
    Antimicrob Agents Chemother. 2001 Sep;45(9):2460-7 PMID: 11502515
  25. Risk factors for the transmission of methicillin-resistant Staphylococcus aureus in an adult intensive care unit: fitting a model to the data.
    J Infect Dis. 2002 Feb 15;185(4):481-8 PMID: 11865400
  26. Staphylococcus aureus resistant to vancomycin--United States, 2002.
    MMWR Morb Mortal Wkly Rep. 2002 Jul 5;51(26):565-7 PMID: 12139181
  27. Rotation and restricted use of antibiotics in a medical intensive care unit. Impact on the incidence of ventilator-associated pneumonia caused by antibiotic-resistant gram-negative bacteria.
    Am J Respir Crit Care Med. 2000 Sep;162(3 Pt 1):837-43 PMID: 10988092
  28. Analysis of vancomycin entry into pulmonary lining fluid by bronchoalveolar lavage in critically ill patients.
    Antimicrob Agents Chemother. 1993 Feb;37(2):281-6 PMID: 8452359
  29. Continuation of a randomized, double-blind, multicenter study of linezolid versus vancomycin in the treatment of patients with nosocomial pneumonia.
    Clin Ther. 2003 Mar;25(3):980-92 PMID: 12852712
  30. Intrapulmonary pharmacokinetics of linezolid.
    Antimicrob Agents Chemother. 2002 May;46(5):1475-80 PMID: 11959585
  31. Linezolid resistance in a clinical isolate of Staphylococcus aureus.
    Lancet. 2001 Jul 21;358(9277):207-8 PMID: 11476839
  32. National Nosocomial Infections Surveillance (NNIS) System Report, Data Summary from January 1992-June 2001, issued August 2001.
    Am J Infect Control. 2001 Dec;29(6):404-21 PMID: 11743489
Article Info
Journal
Intensive care medicine
Abbr.
Intensive Care Med
ISSN
0342-4642
Published
2004-03-00
Epub
2004-00-06
Pages
343-6
Language
English
Region
United States
NLM ID
7704851
Subset
IM
Corrections
CommentOn
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