Studies on the mechanism of the Shwartzman-phenomenon; evidence for the participation of polymorphonuclear leucocytes in the phenomenon.
The inhibition of the Shwartzman phenomenon by nitrogen mustard and benzene has been confirmed and investigated further. This inhibition can be correlated with the leucopenia induced by these agents. Evidence is presented indicating that polymorphonuclear leucocytes play an essential role in the preparation of the skin for the Shwartzman phenomenon.
6 references, click to expand
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The clinical and pathologic effects of the nitrogen and sulfur mustards in laboratory animals.Am J Pathol. 1948 Jan;24(1):1-47 PMID: 18921345
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The carbohydrate metabolism of certain pathological overgrowths.Biochem J. 1928;22(5):1289-98 PMID: 16744142
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Studies on the mechanism of action of the nitrogen and sulfur mustards in vivo.Am J Pathol. 1948 Mar;24(2):275-91 PMID: 18904643
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PATHOLOGIC HISTOLOGY OF THE SHWARTZMAN PHENOMENON WITH INTERPRETATIVE COMMENTS.J Exp Med. 1934 Jun 30;60(1):37-48 PMID: 19870284
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Suppression of local tissue reactivity, Shwartzman phenomenon, by nitrogen mustard, benzol, and X-ray irradiation.Proc Soc Exp Biol Med. 1948 Nov;69(2):247-50 PMID: 18102192
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Studies on the mechanism of the Shwartzman phenomenon.J Exp Med. 1949 May;89(5):461-78 PMID: 18120089
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