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PMID: 1504615 Published · ppublish English Journal Article Review

Genome mapping: cDNA approaches.

Current opinion in genetics & development ·Vol. 2 ·No. 3 ·1992-06-00 ·Pages 412-6

Southern EM

Abstract

Clones of cDNAs have several practical advantages as start points for making physical maps of genomes: they are mainly single copy; they expand the map because of the introns in the genomic version of the gene; and they are conserved between species. They also address biologically important regions of the genome. Sequence information helps to identify new gene functions.

MeSH Terms
Animals Chromosome Mapping/methods Gene Library Genome Genome, Human Humans Organ Specificity RNA, Messenger/genetics
Chemicals
RNA, Messenger
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Southern E M
Department of Biochemistry, Oxford University, UK.
Article Info
Journal
Current opinion in genetics & development
Abbr.
Curr Opin Genet Dev
ISSN
0959-437X
Published
1992-06-00
Pages
412-6
Language
English
Region
England
NLM ID
9111375
Subset
IM
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