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PMID: 15155248 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

IMP-1 and a novel metallo-beta-lactamase, VIM-6, in fluorescent pseudomonads isolated in Singapore.

Antimicrobial agents and chemotherapy ·Vol. 48 ·No. 6 ·2004-06-00 ·页码 2334-6

Koh TH, Wang GC, Sng LH

Abstract

Four carbapenem-resistant Pseudomonas spp. were isolated from patients in Singapore. One Pseudomonas putida isolate contained a bla(IMP-1) identical to that first described in Japan. The sequence of a variant bla(IMP-1) in Pseudomonas fluorescens contained four silent mutations compared with the original sequence. The remaining P. putida isolates contained bla(VIM-6), a novel VIM gene variant.

MeSH 主题词

Amino Acid Sequence Blotting, Southern Conjugation, Genetic DNA, Bacterial/genetics Drug Resistance, Bacterial Isoelectric Focusing Molecular Sequence Data Plasmids/genetics Pseudomonas Infections/microbiology Pseudomonas fluorescens/drug effects,enzymology Pseudomonas putida/drug effects,enzymology Reverse Transcriptase Polymerase Chain Reaction Singapore beta-Lactamases/metabolism

化学物质

DNA, Bacterial beta-lactamase IMP-1 beta-Lactamases

作者与单位

共 3 位作者，点击展开单位 / ORCID

Koh Tse Hsien

Department of Pathology, Singapore General Hospital, 1 Hospital Dr., 168608 Singapore, Singapore. [email protected]

Wang Grace Chee Yeng

Sng Li-Hwei

Article Info

Journal

Antimicrobial agents and chemotherapy

Abbr.

Antimicrob Agents Chemother

ISSN

0066-4804

DOI

10.1128/AAC.48.6.2334-2336.2004

Corresponding email

[email protected]

Published

2004-06-00

页码

2334-6

Language

English

Country/Region

United States

NLM ID

0315061

数据资源

GENBANK

AY165025, AY250709, AY251052

External Links

PubMed source DOI: 10.1128/AAC.48.6.2334-2336.2004 View journal details

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IMP-1 and a novel metallo-beta-lactamase, VIM-6, in fluorescent pseudomonads isolated in Singapore.

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