Increased beta-Secretase activity in cerebrospinal fluid of Alzheimer's disease subjects.

Alzheimer Disease/cerebrospinal fluid,enzymology Amyloid Precursor Protein Secretases Aspartic Acid Endopeptidases/antagonists & inhibitors,cerebrospinal fluid Blotting, Western Brain/drug effects,enzymology Case-Control Studies Cell Line Enzyme Inhibitors/pharmacology Humans Postmortem Changes Time Factors Transfection

Enzyme Inhibitors Amyloid Precursor Protein Secretases Aspartic Acid Endopeptidases