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PMID: 15240873 Published · ppublish English Comment Journal Article Research Support, U.S. Gov't, P.H.S. Review

IL-1beta: an endosomal exit.

Proceedings of the National Academy of Sciences of the United States of America ·Vol. 101 ·No. 28 ·2004-07-13 ·Pages 10241-2

Wewers MD

Abstract

暂无摘要

MeSH Terms
Endosomes/immunology,metabolism Humans Interleukin-1/metabolism Macrophages/metabolism Monocytes/metabolism
Chemicals
Interleukin-1
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Wewers Mark D
Davis Heart and Lung Research Institute, Ohio State University, Columbus, OH 43210, USA. [email protected]
References (23)
23 references, click to expand
  1. Potassium regulates IL-1 beta processing via calcium-independent phospholipase A2.
    J Immunol. 2000 May 15;164(10):5120-4 PMID: 10799869
  2. Spontaneous human monocyte apoptosis utilizes a caspase-3-dependent pathway that is blocked by endotoxin and is independent of caspase-1.
    J Immunol. 1999 Aug 15;163(4):1755-62 PMID: 10438906
  3. Proinflammatory cytokines.
    Chest. 2000 Aug;118(2):503-8 PMID: 10936147
  4. ATP-stimulated release of interleukin (IL)-1beta and IL-18 requires priming by lipopolysaccharide and is independent of caspase-1 cleavage.
    J Biol Chem. 2001 Feb 9;276(6):3820-6 PMID: 11056157
  5. Plant pathogens and integrated defence responses to infection.
    Nature. 2001 Jun 14;411(6839):826-33 PMID: 11459065
  6. Rapid secretion of interleukin-1beta by microvesicle shedding.
    Immunity. 2001 Nov;15(5):825-35 PMID: 11728343
  7. Crucial role of interleukin-1beta and nitric oxide synthase in silica-induced inflammation and apoptosis in mice.
    Am J Respir Crit Care Med. 2002 Feb 15;165(4):527-33 PMID: 11850347
  8. NALPs: a novel protein family involved in inflammation.
    Nat Rev Mol Cell Biol. 2003 Feb;4(2):95-104 PMID: 12563287
  9. P2X7 receptor-dependent blebbing and the activation of Rho-effector kinases, caspases, and IL-1 beta release.
    J Immunol. 2003 Jun 1;170(11):5728-38 PMID: 12759456
  10. NODs: intracellular proteins involved in inflammation and apoptosis.
    Nat Rev Immunol. 2003 May;3(5):371-82 PMID: 12766759
  11. Phospholipases C and A2 control lysosome-mediated IL-1 beta secretion: Implications for inflammatory processes.
    Proc Natl Acad Sci U S A. 2004 Jun 29;101(26):9745-50 PMID: 15192144
  12. Relationship between production and release of lymphocyte-activating factor (interleukin 1) by murine macrophages. 1. Effects of various agents.
    Cell Immunol. 1981 Nov 1;64(2):293-303 PMID: 6272997
  13. Silica enhancement of murine endotoxin sensitivity.
    Infect Immun. 1982 Nov;38(2):681-5 PMID: 6183219
  14. Silica-stimulated monocytes release fibroblast proliferation factors identical to interleukin 1. A potential role for interleukin 1 in the pathogenesis of silicosis.
    J Clin Invest. 1984 May;73(5):1462-72 PMID: 6325504
  15. Normal human alveolar macrophages obtained by bronchoalveolar lavage have a limited capacity to release interleukin-1.
    J Clin Invest. 1984 Dec;74(6):2208-18 PMID: 6334697
  16. Subcellular localization of human monocyte interleukin 1: evidence for an inactive precursor molecule and a possible mechanism for IL 1 release.
    J Immunol. 1987 Jun 15;138(12):4249-55 PMID: 3495584
  17. Interleukin 1 is processed and released during apoptosis.
    Proc Natl Acad Sci U S A. 1991 Oct 1;88(19):8485-9 PMID: 1924307
  18. Signal transduction via P2-purinergic receptors for extracellular ATP and other nucleotides.
    Am J Physiol. 1993 Sep;265(3 Pt 1):C577-606 PMID: 8214015
  19. The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme.
    Cell. 1993 Nov 19;75(4):641-52 PMID: 8242740
  20. Interleukin-1 beta maturation and release in response to ATP and nigericin. Evidence that potassium depletion mediated by these agents is a necessary and common feature of their activity.
    J Biol Chem. 1994 May 27;269(21):15195-203 PMID: 8195155
  21. ATP induces the release of IL-1 from LPS-primed cells in vivo.
    J Immunol. 1995 Mar 15;154(6):2821-8 PMID: 7876552
  22. Post-translational processing of murine IL-1: evidence that ATP-induced release of IL-1 alpha and IL-1 beta occurs via a similar mechanism.
    J Immunol. 1998 Mar 1;160(5):2469-77 PMID: 9498792
  23. The secretory route of the leaderless protein interleukin 1beta involves exocytosis of endolysosome-related vesicles.
    Mol Biol Cell. 1999 May;10(5):1463-75 PMID: 10233156
Article Info
Journal
Proceedings of the National Academy of Sciences of the United States of America
Abbr.
Proc Natl Acad Sci U S A
ISSN
0027-8424
DOI
10.1073/pnas.0403971101
Email
[email protected]
Published
2004-07-13
Epub
2004-00-06
Pages
10241-2
Language
English
Region
United States
NLM ID
7505876
PMCID
PMC478557
Subset
IM
Grants
NHLBI NIH HHS · R01 HL040871 · United States
Corrections
CommentOn
PMID: 15192144
External Links
PubMed source DOI: 10.1073/pnas.0403971101 PMC Full Text View journal details
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