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PMID: 1531727 Published · ppublish English Historical Article Journal Article Research Support, Non-U.S. Gov't Review

Huntington disease and the abuse of genetics.

American journal of human genetics ·Vol. 50 ·No. 3 ·1992-03-00 ·Pages 460-4

Harper PS

Abstract

Huntington disease, one of the longest established and most serious human genetic disorders, has been the subject of considerable abuse during the present century in relation to the application of genetic knowledge, most notably in Nazi Germany but also in other countries. This disorder provides a valuable example of how abuses in the past need to be recognized and confronted, if we are to avoid their recurrence in relation to new molecular and computing techniques in genetics.

Keywords
Genetics and Reproduction
MeSH Terms
Eugenics/history,legislation & jurisprudence Germany History, 20th Century Human Rights Humans Huntington Disease/genetics,history Internationality National Socialism Professional Misconduct Sterilization, Reproductive/history United States
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Harper P S
Institute of Medical Genetics, University of Wales College of Medicine, Cardiff, United Kingdom.
References (6)
6 references, click to expand
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    Obstet Gynecol Clin North Am. 1990 Sep;17(3):651-68 PMID: 2247296
  3. Presymptomatic diagnosis of delayed-onset disease with linked DNA markers. The experience in Huntington's disease.
    JAMA. 1989 Jun 2;261(21):3108-14 PMID: 2523979
  4. The fate of the mentally ill in Germany during the Third Reich.
    Psychol Med. 1988 Aug;18(3):575-81 PMID: 3054989
  5. Huntington disease: no evidence for locus heterogeneity.
    Genomics. 1989 Aug;5(2):304-8 PMID: 2571579
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    Lancet. 1988 Nov 5;2(8619):1069-70 PMID: 2903290
Article Info
Journal
American journal of human genetics
Abbr.
Am J Hum Genet
ISSN
0002-9297
Published
1992-03-00
Pages
460-4
Language
English
Region
United States
NLM ID
0370475
PMCID
PMC1684272
Subset
IM
Corrections
CommentIn
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