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PMID: 15372043 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Review

RNA silencing in plants.

Nature ·Vol. 431 ·No. 7006 ·2004-09-16 ·Pages 356-63

Baulcombe D

Abstract

There are at least three RNA silencing pathways for silencing specific genes in plants. In these pathways, silencing signals can be amplified and transmitted between cells, and may even be self-regulated by feedback mechanisms. Diverse biological roles of these pathways have been established, including defence against viruses, regulation of gene expression and the condensation of chromatin into heterochromatin. We are now in a good position to investigate the full extent of this functional diversity in genetic and epigenetic mechanisms of genome control.

MeSH Terms
Arabidopsis Proteins/genetics,metabolism Argonaute Proteins Gene Expression Regulation, Plant MicroRNAs/genetics,metabolism Plants/genetics,virology RNA Interference/physiology RNA, Plant/genetics,metabolism Ribonuclease III/genetics,metabolism
Chemicals
AGO1 protein, Arabidopsis Arabidopsis Proteins Argonaute Proteins MicroRNAs RNA, Plant Ribonuclease III
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Baulcombe David
The Sainsbury Laboratory, John Innes Centre, Colney Lane, Norwich NR4 7UH, UK. [email protected]
Article Info
Journal
Nature
Abbr.
Nature
ISSN
1476-4687
Published
2004-09-16
Pages
356-63
Language
English
Region
England
NLM ID
0410462
Subset
IM
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