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PMID: 1541540 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Serological relationship of tumor necrosis factor-inducing exoantigens of Plasmodium falciparum and Plasmodium vivax.

Infection and immunity ·Vol. 60 ·No. 3 ·1992-03-00 ·Pages 1241-3

Bate CA, Taverne J, Karunaweera ND, Mendis KN, Kwiatkowski D, Playfair JH

Abstract

Exoantigens of Plasmodium vivax-parasitized erythrocytes stimulated macrophages to secrete tumor necrosis factor, and antisera raised against the exoantigens inhibited this secretion. The antisera also inhibited the activity of Plasmodium falciparum and Plasmodium yoelii exoantigens, and conversely, antisera against the latter cross-reacted with the exoantigens of P. vivax.

MeSH Terms
Animals Antigens, Protozoan/immunology Humans Immune Sera/immunology Plasmodium falciparum/immunology Plasmodium vivax/immunology Tumor Necrosis Factor-alpha/biosynthesis
Chemicals
Antigens, Protozoan Immune Sera Tumor Necrosis Factor-alpha
Authors & Affiliations
6 authors, click to expand affiliations / ORCID
Bate C A
Department of Immunology, University College and Middlesex School of Medicine, London, United Kingdom.
Taverne J
Karunaweera N D
Mendis K N
Kwiatkowski D
Playfair J H
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17 references, click to expand
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Article Info
Journal
Infection and immunity
Abbr.
Infect Immun
ISSN
0019-9567
DOI
10.1128/iai.60.3.1241-1243.1992
Published
1992-03-00
Pages
1241-3
Language
English
Region
United States
NLM ID
0246127
PMCID
PMC257621
Subset
IM
External Links
PubMed source DOI: 10.1128/iai.60.3.1241-1243.1992 PMC Full Text View journal details
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