On the nature of the toxic component of the somatic antigen of Shigella paradysenteriae type Z (Flexner).
From the chemical evidence presented it appears that the toxicity associated with the somatic antigen of Type Z Sh. paradysenteriae may be attributed to an entity distinct from the known components of the complex. That this substance is neither the protein, the lipid, nor the carbohydrate component of the antigen is evident. Because of its lability to chemical manipulation, the nature of the toxic component, has not yet been ascertained.
7 references, click to expand
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Studies in immunochemistry: The fractionation and nature of antigenic material isolated from Bact. dysenteriae (Shiga).Biochem J. 1940 Feb;34(2):169-91 PMID: 16747152
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The estimation of phosphorus.Biochem J. 1940 Jun;34(6):858-65 PMID: 16747230
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Further studies of the immunological properties of polysaccharides from Serratia marcescens (Bacillus prodigiosus) the effects of passive and active immunization on the lethal activity of the polysaccharides.Cancer Res. 1949 Mar;9(3):150-7 PMID: 18113450
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STUDIES ON THE FLEXNER GROUP OF DYSENTERY BACILLI : I. THE SPECIFIC ANTIGENS OF SHIGELLA PARADYSENTERIAE (FLEXNER).J Exp Med. 1945 Apr 1;81(4):315-30 PMID: 19871460
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STUDIES ON THE FLEXNER GROUP OF DYSENTERY BACILLI : II. THE CHEMICAL DEGRADATION OF THE SPECIFIC ANTIGEN OF TYPE Z SHIGELLA PARADYSENTERIAE (FLEXNER).J Exp Med. 1945 Apr 1;81(4):331-47 PMID: 19871461
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STUDIES ON THE FLEXNER GROUP OF DYSENTERY BACILLI : V. A QUANTITATIVE STUDY OF THE SEROLOGICAL CROSS-REACTIONS.J Exp Med. 1946 Aug 31;84(3):235-45 PMID: 19871567
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Studies in immuno-chemistry: The isolation and properties of a specific antigenic substance from B. dysenteriae (Shiga).Biochem J. 1937 Nov;31(11):2003-21 PMID: 16746543
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