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PMID: 1547917 Published · ppublish English Comparative Study Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

The incidence of male childhood type 1 (insulin-dependent) diabetes mellitus is rising rapidly in The Netherlands.

Diabetologia ·Vol. 35 ·No. 2 ·1992-02-00 ·Pages 139-42

Drykoningen CE, Mulder AL, Vaandrager GJ, LaPorte RE, Bruining GJ

Abstract

This study evaluates the cumulative incidence of Type 1 (insulin-dependent) diabetes mellitus in male army conscripts 0-18 (inclusive) years of age in the Netherlands (birth cohorts) over 10 years. Data from 2136 cases were retrieved from files of the conscript registry of the Royal Dutch Army. Ascertainment was sought by the capture-recapture method, achieving an average ascertainment rate of 89.7%. Poisson regression modelling was used to determine the change in incidence over time. A significant non-linear increase in the incidence of insulin-dependency in the birth cohorts of 1960-1970 was found. The cumulative incidences of the early birth cohorts 1.85/1000 (1960), 1.76/1000 (1961), 1.11/1000 (1962) were considerably lower than of the later birth cohorts 1.96/1000 (1968), 2.11/1000 (1969), 2.12/1000 (1970). Overall the risk of Type 1 diabetes increased on the average 4.4% with each annual birth cohort. Only for the 1962 birth cohort was a significant dip in the incidence observed. The results indicate a rapidly increasing incidence of diabetes in males in the Netherlands consistent with the concurrent rapid rise in Northern Europe, found in both sexes.

MeSH Terms
Adolescent Child Cohort Studies Diabetes Mellitus, Type 1/epidemiology Humans Incidence Male Military Personnel Netherlands/epidemiology
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Drykoningen C E
TNO Institute for Preventive Health Care, Leiden, The Netherlands.
Mulder A L
Vaandrager G J
LaPorte R E
Bruining G J
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18 references, click to expand
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Article Info
Journal
Diabetologia
Abbr.
Diabetologia
ISSN
0012-186X
Published
1992-02-00
Pages
139-42
Language
English
Region
Germany
NLM ID
0006777
Subset
IM
Grants
NIDDK NIH HHS · DK24021 · United States
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