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PMID: 15508014 Published · ppublish English Clinical Trial Journal Article Randomized Controlled Trial Research Support, Non-U.S. Gov't

Lupin kernel fibre-enriched foods beneficially modify serum lipids in men.

European journal of clinical nutrition ·Vol. 59 ·No. 3 ·2005-03-00 ·Pages 325-33

Hall RS, Johnson SK, Baxter AL, Ball MJ

Abstract

To examine the effect of a diet containing a novel legume food ingredient, Australian sweet lupin (Lupinus angustifolius) kernel fibre (LKFibre), compared to a control diet without the addition of LKFibre, on serum lipids in men. Randomized crossover dietary intervention study. Melbourne, Australia--Free-living men. A total of 38 healthy males between the ages of 24 and 64 y completed the intervention. Subjects consumed an LKFibre and a control diet for 1 month each. Both diets had the same background menus with seven additional experimental foods that either contained LKFibre or did not. Depending on energy intake, the LKFibre diet was designed to contain an additional 17 to 30 g/day fibre beyond that of the control diet. Compared to the control diet, the LKFibre diet reduced total cholesterol (TC) (mean+/-s.e.m.; 4.5+/-1.7%; P=0.001), low-density lipoprotein cholesterol (LDL-C) (5.4+/-2.2%; P=0.001), TC: high-density lipoprotein cholesterol (HDL-C) (3.0+/-2.0%; P=0.006) and LDL-C:HDL-C (3.8+/-2.6%; P=0.003). No effects on HDL-C, triacylglycerols, glucose or insulin were observed. Addition of LKFibre to the diet provided favourable changes to some serum lipid measures in men, which, combined with its high palatability, suggest this novel ingredient may be useful in the dietary reduction of coronary heart disease risk.

MeSH Terms
Adult Cholesterol/blood Cholesterol, HDL/blood Cholesterol, LDL/blood Coronary Disease/blood,prevention & control Cross-Over Studies Dietary Fiber/administration & dosage,therapeutic use Humans Hypercholesterolemia/blood,drug therapy Lupinus/chemistry Male Middle Aged Phytotherapy Triglycerides/blood
Chemicals
Cholesterol, HDL Cholesterol, LDL Dietary Fiber Triglycerides Cholesterol
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Hall R S
School of Exercise and Nutrition Sciences, Deakin University, Burwood, Victoria, Australia.
Johnson S K
Baxter A L
Ball M J
Article Info
Journal
European journal of clinical nutrition
Abbr.
Eur J Clin Nutr
ISSN
0954-3007
Published
2005-03-00
Pages
325-33
Language
English
Region
England
NLM ID
8804070
Subset
IM
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