A new gene of the f1 operon of Y. pestis involved in the capsule biogenesis.

FEBS letters ·Vol. 297 ·No. 1-2 ·1992-02-03 ·Pages 77-80

Karlyshev AV, Galyov EE, Smirnov OYu, Guzayev AP, Abramov VM, Zav'yalov VP

Abstract

The DNA sequence determination of the f1 operon between the genes encoding the F1 subunit (caf1) and chaperone-like protein (caf1M) revealed a large open reading frame that codes for a polypeptide similar to some E. coli proteins involved in the biogenesis of fimbria. The deletion and in trans complementation analyses showed that this gene is not necessary for extracellular transport of the F1 subunit but plays a role in the capsule assembly.

Related Genes

caf1 f1

MeSH Terms

Amino Acid Sequence Bacterial Capsules/biosynthesis Base Sequence DNA, Bacterial/genetics Genes, Bacterial Genetic Complementation Test Molecular Sequence Data Operon Plasmids Restriction Mapping Sequence Alignment Yersinia pestis/genetics

Chemicals

DNA, Bacterial

Authors & Affiliations

6 authors, click to expand affiliations / ORCID

Karlyshev A V

Institute of Immunology, State Concern Biopreparation, Lyubuchany, Moscow Region, USSR.

Galyov E E

Smirnov OYu

Guzayev A P

Abramov V M

Zav'yalov V P

Article Info

Journal

FEBS letters

Abbr.

FEBS Lett

ISSN

0014-5793

DOI

10.1016/0014-5793(92)80331-a

Published

1992-02-03

Pages

77-80

Language

English

Region

England

NLM ID

0155157

Subset

Databases

GENBANK

S90282, S90283, S90285, S90286, S90288, S90290, S90294, S90296, S90298, X61996

External Links

PubMed source DOI: 10.1016/0014-5793(92)80331-a View journal details

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A new gene of the f1 operon of Y. pestis involved in the capsule biogenesis.

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