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PMID: 15625857 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.

Inhibition of E. coli beta-hydroxydecanoyl thioester dehydrase by ppGpp.

Biochemical and biophysical research communications ·Vol. 73 ·No. 4 ·1976-12-20 ·Pages 881-4

Stein JP, Bloch KE

Abstract

Guanosine-5'-diphosphate-3'-diphosphate was found to inhibit beta-hydroxydecanoyl thioester dehydrase of E. coli at concentrations corresponding to those generated in vivo during amino acid starvation of rel+ cells.

MeSH Terms
Enzyme Inhibitors/pharmacology Escherichia coli/enzymology Fatty Acid Synthase, Type II Guanosine Tetraphosphate/pharmacology Hydro-Lyases/antagonists & inhibitors,metabolism
Chemicals
Enzyme Inhibitors Guanosine Tetraphosphate Hydro-Lyases 3-hydroxyacyl-(acyl-carrier-protein) dehydratase Fatty Acid Synthase, Type II
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Stein J P
James Bryant Conant Laboratory, Harvard University, Cambridge, Massachusetts 02138, USA.
Bloch K E
Article Info
Journal
Biochemical and biophysical research communications
Abbr.
Biochem Biophys Res Commun
ISSN
0006-291X
DOI
10.1016/0006-291x(76)90204-7
Published
1976-12-20
Pages
881-4
Language
English
Region
United States
NLM ID
0372516
Subset
IM
External Links
PubMed source DOI: 10.1016/0006-291x(76)90204-7 View journal details
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