LDL size: does it matter?

Swiss medical weekly ·Vol. 134 ·No. 49-50 ·2004-12-18 ·Pages 720-4

Berneis K, Rizzo M

Abstract

The atherogenic lipoprotein phenotype is characterised by a moderate increase in plasma triglycerides, a decrease in high density lipoprotein cholesterol and the prevalence of smaller denser low density lipoprotein particles. The prevalence of this partially inheritable phenotype is approximately 30% and is a feature of the metabolic syndrome associated with an increased risk for cardiovascular events. The predominance of small dense LDL has been accepted as an emerging cardiovascular risk factor by the adult treatment panel (ATP) III.

MeSH Terms

Adult Age Factors Aged Animals Arteriosclerosis/blood,etiology,genetics Cholesterol, LDL/blood Clinical Trials as Topic Cohort Studies Coronary Disease/blood,epidemiology,genetics,prevention & control Diabetes Mellitus/blood,etiology Female Humans Hypolipidemic Agents/therapeutic use Insulin Resistance Lipoproteins, LDL/blood,genetics,metabolism Logistic Models Male Metabolic Syndrome/blood Middle Aged Phenotype Prevalence Prospective Studies Risk Factors Sex Factors Smoking/adverse effects Triglycerides/blood

Chemicals

Cholesterol, LDL Hypolipidemic Agents Lipoproteins, LDL Triglycerides

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Berneis K

University Hospital Bruderholz, Department of Internal Medicine, Switzerland. [email protected]

Rizzo M

Article Info

Journal

Swiss medical weekly

Abbr.

Swiss Med Wkly

ISSN

1424-7860

DOI

2004/49/smw-10813

[email protected]

Published

2004-12-18

Pages

720-4

Language

English

Region

Switzerland

NLM ID

100970884

Subset

External Links

PubMed source DOI: 2004/49/smw-10813 View journal details

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LDL size: does it matter?

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