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PMID: 15687268 Published · ppublish English Journal Article Research Support, U.S. Gov't, Non-P.H.S.

The evolution of the SEPALLATA subfamily of MADS-box genes: a preangiosperm origin with multiple duplications throughout angiosperm history.

Genetics ·Vol. 169 ·No. 4 ·2005-04-00 ·Pages 2209-23

Zahn LM, Kong H, Leebens-Mack JH, Kim S, Soltis PS, Landherr LL, Soltis DE, Depamphilis CW, Ma H

Abstract

Members of the SEPALLATA (SEP) MADS-box subfamily are required for specifying the "floral state" by contributing to floral organ and meristem identity. SEP genes have not been detected in gymnosperms and seem to have originated since the lineage leading to extant angiosperms diverged from extant gymnosperms. Therefore, both functional and evolutionary studies suggest that SEP genes may have been critical for the origin of the flower. To gain insights into the evolution of SEP genes, we isolated nine genes from plants that occupy phylogenetically important positions. Phylogenetic analyses of SEP sequences show that several gene duplications occurred during the evolution of this subfamily, providing potential opportunities for functional divergence. The first duplication occurred prior to the origin of the extant angiosperms, resulting in the AGL2/3/4 and AGL9 clades. Subsequent duplications occurred within these clades in the eudicots and monocots. The timing of the first SEP duplication approximately coincides with duplications in the DEFICIENS/GLOBOSA and AGAMOUS MADS-box subfamilies, which may have resulted from either a proposed genome-wide duplication in the ancestor of extant angiosperms or multiple independent duplication events. Regardless of the mechanism of gene duplication, these pairs of duplicate transcription factors provided new possibilities of genetic interactions that may have been important in the origin of the flower.

MeSH Terms
Algorithms Amino Acid Sequence Arabidopsis/genetics DNA, Complementary/metabolism Databases, Genetic Evolution, Molecular Gene Duplication Gene Expression Regulation, Plant Gene Library Genes, Plant In Situ Hybridization MADS Domain Proteins/genetics Magnoliopsida/metabolism Models, Genetic Molecular Sequence Data Multigene Family Phylogeny Protein Structure, Tertiary Reverse Transcriptase Polymerase Chain Reaction Sequence Analysis, DNA Sequence Homology, Amino Acid Transcription Factors/genetics
Chemicals
DNA, Complementary MADS Domain Proteins Transcription Factors
Authors & Affiliations
9 authors, click to expand affiliations / ORCID
Zahn Laura M
Department of Biology, Huck Institutes of the Life Sciences, The Pennsylvania State University, University Park, 16802, USA.
Kong Hongzhi
Leebens-Mack James H
Kim Sangtae
Soltis Pamela S
Landherr Lena L
Soltis Douglas E
Depamphilis Claude W
Ma Hong
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Article Info
Journal
Genetics
Abbr.
Genetics
ISSN
0016-6731
DOI
10.1534/genetics.104.037770
Published
2005-04-00
Epub
2005-00-31
Pages
2209-23
Language
English
Region
United States
NLM ID
0374636
PMCID
PMC1449606
Subset
IM
Databases
GENBANK
AY850178, AY850179, AY850180, AY850181, AY850182, AY850183, AY850184, AY850185, AY850186
External Links
PubMed source DOI: 10.1534/genetics.104.037770 PMC Full Text View journal details
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