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PMID: 15772296 Published · ppublish English Journal Article Research Support, N.I.H., Extramural Research Support, U.S. Gov't, P.H.S. Review

Renal cell-to-cell communication via extracellular ATP.

Physiology (Bethesda, Md.) ·Vol. 20 ·2005-04-00 ·Pages 86-90

Komlosi P, Fintha A, Bell PD

Abstract

In the kidney, macula densa cells communicate with the mesangial cell-afferent arteriolar smooth muscle cell complex through ATP signaling. This signaling process involves release of ATP across the macula densa basolateral membrane through a maxi anion channel and the interaction of ATP with purinergic P2 receptors.

MeSH Terms
Adenosine Triphosphate/metabolism Animals Cell Communication/physiology Extracellular Space/metabolism Humans Kidney/cytology,physiology
Chemicals
Adenosine Triphosphate
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Komlosi Peter
Department of Medicine, Division of Nephrology, University of Alabama at Birmingham, Birmingham, Alabama, USA. [email protected]
Fintha Attila
Bell P Darwin
Article Info
Journal
Physiology (Bethesda, Md.)
Abbr.
Physiology (Bethesda)
ISSN
1548-9213
DOI
10.1152/physiol.00002.2005
Email
[email protected]
Published
2005-04-00
Pages
86-90
Language
English
Region
United States
NLM ID
101208185
Subset
IM
Grants
NIDDK NIH HHS · DK-32032 · United States
External Links
PubMed source DOI: 10.1152/physiol.00002.2005 View journal details
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