Proapoptotic regimes for HTLV-I-transformed cells: targeting Tax and the NF-kappaB pathway.

Animals Antineoplastic Agents/administration & dosage Apoptosis/immunology Arsenic Trioxide Arsenicals/administration & dosage Drug Delivery Systems Gene Expression Regulation Gene Products, tax/drug effects,immunology,metabolism Human T-lymphotropic virus 1/immunology,metabolism,pathogenicity Humans Leukemia-Lymphoma, Adult T-Cell/drug therapy,immunology NF-kappa B/antagonists & inhibitors,immunology,metabolism Nitriles/administration & dosage Oxides/administration & dosage Proteasome Inhibitors Sulfones/administration & dosage T-Lymphocytes/immunology,virology

3-(4-methylphenylsulfonyl)-2-propenenitrile Antineoplastic Agents Arsenicals Gene Products, tax NF-kappa B Nitriles Oxides Proteasome Inhibitors Sulfones Arsenic Trioxide