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PMID: 15854678 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

An operator splitting method for solving the bidomain equations coupled to a volume conductor model for the torso.

Mathematical biosciences ·Vol. 194 ·No. 2 ·2005-04-00 ·Pages 233-48

Sundnes J, Lines GT, Tveito A

Abstract

In this paper we present a numerical method for the bidomain model, which describes the electrical activity in the heart. The model consists of two partial differential equations (PDEs), which are coupled to systems of ordinary differential equations (ODEs) describing electrochemical reactions in the cardiac cells. Many applications require coupling these equations to a third PDE, describing the electrical fields in the torso surrounding the heart. The resulting system is challenging to solve numerically, because of its complexity and very strict resolution requirements in time and space. We propose a method based on operator splitting and a fully coupled discretization of the three PDEs. Numerical experiments show that for simple simulation cases and fine discretizations, the algorithm is second-order accurate in space and time.

MeSH Terms
Algorithms Computer Simulation Electric Capacitance Electric Conductivity Electrochemistry Electrophysiology Heart/physiology Humans Models, Cardiovascular Myocytes, Cardiac/physiology
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Sundnes Joakim
Simula Research Laboratory and University of Oslo, P.O. Box 134, NO-1325 Lysaker, Norway. [email protected]
Lines Glenn Terje
Tveito Aslak
Article Info
Journal
Mathematical biosciences
Abbr.
Math Biosci
ISSN
0025-5564
Published
2005-04-00
Pages
233-48
Language
English
Region
United States
NLM ID
0103146
Subset
IM
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