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PMID: 15904266 Published · ppublish English Journal Article

Scale-rich metabolic networks.

Physical review letters ·Vol. 94 ·No. 16 ·2005-04-29 ·Pages 168101

Tanaka R

Abstract

Recent research in biology has clarified many features of the global organization of metabolic networks, including the biochemical mechanisms responsible for power laws in metabolite degrees. The primary aim of this Letter is to give the simplest possible biochemical explanations and minimal toy models based on a highly optimized tolerance perspective, which show where and why metabolic networks have power laws. A second aim is to further explain why scale-free explanations fail in this case to correctly describe metabolism.

MeSH Terms
Adenosine Diphosphate/metabolism Adenosine Triphosphate/metabolism Amino Acids/biosynthesis Helicobacter pylori/enzymology,metabolism Models, Biological NAD/metabolism
Chemicals
Amino Acids NAD Adenosine Diphosphate Adenosine Triphosphate
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Tanaka Reiko
Bio-Mimetic Control Research Center, RIKEN, Moriyama-ku, Nagoya 463-0003, Japan. [email protected]
Article Info
Journal
Physical review letters
Abbr.
Phys Rev Lett
ISSN
0031-9007
Published
2005-04-29
Epub
2005-00-25
Pages
168101
Language
English
Region
United States
NLM ID
0401141
Subset
IM
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