Home LiteratureArticle Details
PMID: 15987607 Published · ppublish English Journal Article Review

Hippocampal function, declarative memory, and schizophrenia: anatomic and functional neuroimaging considerations.

Current neurology and neuroscience reports ·Vol. 5 ·No. 4 ·2005-07-00 ·Pages 249-56

Preston AR, Shohamy D, Tamminga CA, Wagner AD

Abstract

暂无摘要

MeSH Terms
Animals Diagnostic Imaging Entorhinal Cortex/pathology,physiopathology Hippocampus/anatomy & histology,physiology Humans Memory/physiology Neural Pathways/pathology,physiopathology Parahippocampal Gyrus/pathology,physiopathology Schizophrenia/pathology,physiopathology
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Preston Alison R
Psychology Department, Stanford University, Jordan Hall, Building 420, Stanford, CA 94305-2130, USA.
Shohamy Daphna
Tamminga Carol A
Wagner Anthony D
References (108)
108 references, click to expand
  1. Some connections of the entorhinal (area 28) and perirhinal (area 35) cortices of the rhesus monkey. I. Temporal lobe afferents.
    Brain Res. 1975 Sep 12;95(1):1-24 PMID: 1156859
  2. Developmental Processes in Schizophrenic Disorders: longitudinal studies of vulnerability and stress.
    Schizophr Bull. 1992;18(3):387-425 PMID: 1411329
  3. Impaired hippocampal recruitment during normal modulation of memory performance in schizophrenia.
    Biol Psychiatry. 2003 Jan 1;53(1):48-55 PMID: 12513944
  4. Working memory dysfunction in schizophrenia.
    J Neuropsychiatry Clin Neurosci. 1994 Fall;6(4):348-57 PMID: 7841806
  5. Topographical organization of the entorhinal projection to the dentate gyrus of the monkey.
    J Neurosci. 1989 Jan;9(1):216-28 PMID: 2913203
  6. Resting cerebral glucose metabolism in first-episode and previously treated patients with schizophrenia relates to clinical features.
    Arch Gen Psychiatry. 1995 Aug;52(8):657-67 PMID: 7632119
  7. Perirhinal and parahippocampal cortices of the macaque monkey: cortical afferents.
    J Comp Neurol. 1994 Dec 22;350(4):497-533 PMID: 7890828
  8. Simple and associative recognition memory in the hippocampal region.
    Learn Mem. 2001 Jul-Aug;8(4):190-7 PMID: 11533222
  9. Glutamate receptors and transporters in the hippocampus in schizophrenia.
    Ann N Y Acad Sci. 2003 Nov;1003:94-101 PMID: 14684437
  10. The generalized pattern of neuropsychological deficits in outpatients with chronic schizophrenia with heterogeneous Wisconsin Card Sorting Test results.
    Arch Gen Psychiatry. 1991 Oct;48(10):891-8 PMID: 1929758
  11. Neuroimaging of hallucinations: a review of the literature.
    Psychiatry Res. 1999 Dec 20;92 (2-3):61-74 PMID: 10674360
  12. Hippocampal contribution to the novel use of relational information in declarative memory.
    Hippocampus. 2004;14(2):148-52 PMID: 15098720
  13. Memory orientation and success: separable neurocognitive components underlying episodic recognition.
    Neuropsychologia. 2003;41(3):318-33 PMID: 12457757
  14. Limbic system abnormalities identified in schizophrenia using positron emission tomography with fluorodeoxyglucose and neocortical alterations with deficit syndrome.
    Arch Gen Psychiatry. 1992 Jul;49(7):522-30 PMID: 1627043
  15. Impairments on neuropsychologic tests of temporohippocampal and frontohippocampal functions and word fluency in remitting schizophrenia and affective disorders.
    Arch Gen Psychiatry. 1988 Jul;45(7):623-9 PMID: 3382322
  16. Frontostriatal disorder of cerebral metabolism in never-medicated schizophrenics.
    Arch Gen Psychiatry. 1992 Dec;49(12 ):935-42 PMID: 1360198
  17. NMDA receptors, place cells and hippocampal spatial memory.
    Nat Rev Neurosci. 2004 May;5(5):361-72 PMID: 15100719
  18. The hippocampus and memory for orderly stimulus relations.
    Proc Natl Acad Sci U S A. 1997 Jun 24;94(13):7109-14 PMID: 9192700
  19. Neuropsychological function in schizophrenia. Selective impairment in memory and learning.
    Arch Gen Psychiatry. 1991 Jul;48(7):618-24 PMID: 2069492
  20. Loss of recent memory after bilateral hippocampal lesions.
    J Neurol Neurosurg Psychiatry. 1957 Feb;20(1):11-21 PMID: 13406589
  21. Functional abnormalities of medial temporal cortex during novel picture learning among patients with chronic schizophrenia.
    Schizophr Res. 2003 Feb 1;59(2-3):187-98 PMID: 12414075
  22. Further evidence for dementia of the prefrontal type in schizophrenia? A controlled study of teaching the Wisconsin Card Sorting Test.
    Arch Gen Psychiatry. 1987 Nov;44(11):1008-14 PMID: 3675128
  23. Temporal and cerebellar brain regions that support both declarative memory formation and retrieval.
    Cereb Cortex. 2004 Mar;14(3):256-67 PMID: 14754866
  24. A functional neuroanatomy of hallucinations in schizophrenia.
    Nature. 1995 Nov 9;378(6553):176-9 PMID: 7477318
  25. Impaired speed of information processing in nonmedicated schizotypal patients.
    Schizophr Bull. 1981;7(3):499-508 PMID: 7280576
  26. Observing the transformation of experience into memory.
    Trends Cogn Sci. 2002 Feb 1;6(2):93-102 PMID: 15866193
  27. Hippocampal deformities in schizophrenia characterized by high dimensional brain mapping.
    Am J Psychiatry. 2002 Dec;159(12):2000-6 PMID: 12450948
  28. Hippocampal contributions to episodic encoding: insights from relational and item-based learning.
    J Neurophysiol. 2002 Aug;88(2):982-90 PMID: 12163547
  29. Dissociable correlates of recollection and familiarity within the medial temporal lobes.
    Neuropsychologia. 2004;42(1):2-13 PMID: 14615072
  30. Phenotype of schizophrenia: a review and formulation.
    Mol Psychiatry. 2005 Jan;10(1):27-39 PMID: 15340352
  31. Neuropathological studies of synaptic connectivity in the hippocampal formation in schizophrenia.
    Hippocampus. 2001;11(5):508-19 PMID: 11732704
  32. Separate neural bases of two fundamental memory processes in the human medial temporal lobe.
    Science. 1997 Apr 11;276(5310):264-6 PMID: 9092477
  33. Cortical inputs to the CA1 field of the monkey hippocampus originate from the perirhinal and parahippocampal cortex but not from area TE.
    Neurosci Lett. 1990 Jul 17;115(1):43-8 PMID: 1699176
  34. The left medial temporal region and schizophrenia. A PET study.
    Brain. 1992 Apr;115 ( Pt 2):367-82 PMID: 1606474
  35. Associative recognition in a patient with selective hippocampal lesions and relatively normal item recognition.
    Hippocampus. 2004;14(6):763-84 PMID: 15318334
  36. Modeling hippocampal and neocortical contributions to recognition memory: a complementary-learning-systems approach.
    Psychol Rev. 2003 Oct;110(4):611-46 PMID: 14599236
  37. Hippocampal deformities in the unaffected siblings of schizophrenia subjects.
    Biol Psychiatry. 2003 Dec 1;54(11):1234-40 PMID: 14643091
  38. Anterior hippocampal volume reductions predict frontal lobe dysfunction in first episode schizophrenia.
    Schizophr Res. 1995 Sep;17(1):47-58 PMID: 8541249
  39. Hippocampal activation during transitive inference in humans.
    Hippocampus. 2004;14(2):153-62 PMID: 15098721
  40. Recognition memory and the human hippocampus.
    Neuron. 2003 Jan 9;37(1):171-80 PMID: 12526782
  41. Topographic organization of the reciprocal connections between the monkey entorhinal cortex and the perirhinal and parahippocampal cortices.
    J Neurosci. 1994 Mar;14(3 Pt 2):1856-77 PMID: 8126576
  42. Evidence for the validity of negative symptoms.
    Mod Probl Pharmacopsychiatry. 1990;24:43-72 PMID: 2186268
  43. Entorhinal cortex of the monkey: V. Projections to the dentate gyrus, hippocampus, and subicular complex.
    J Comp Neurol. 1991 May 15;307(3):437-59 PMID: 1713237
  44. Neuropsychological functioning in siblings discordant for schizophrenia and healthy volunteers.
    Arch Gen Psychiatry. 1994 Aug;51(8):651-61 PMID: 8042914
  45. The entorhinal cortex of the monkey: I. Cytoarchitectonic organization.
    J Comp Neurol. 1987 Oct 15;264(3):326-55 PMID: 2445795
  46. Impaired recognition memory on the Doors and People Test after damage limited to the hippocampal region.
    Hippocampus. 1999;9(5):495-9 PMID: 10560919
  47. Memory and the hippocampus: a synthesis from findings with rats, monkeys, and humans.
    Psychol Rev. 1992 Apr;99(2):195-231 PMID: 1594723
  48. Functional MRI and novel picture-learning among older patients with chronic schizophrenia: abnormal correlations between recognition memory and medial temporal brain response.
    Am J Geriatr Psychiatry. 2002 Jan-Feb;10(1):52-61 PMID: 11790635
  49. Regional cerebral blood flow in patients with schizophrenia. A preliminary report.
    Eur Arch Psychiatry Clin Neurosci. 1992;241(4):195-200 PMID: 1576174
  50. Hippocampal, parahippocampal and occipital-temporal contributions to associative and item recognition memory: an fMRI study.
    Neuroreport. 2001 Feb 12;12(2):359-63 PMID: 11209950
  51. Evidence for altered trisynaptic circuitry in schizophrenic hippocampus.
    Biol Psychiatry. 1999 Sep 1;46(5):589-99 PMID: 10472413
  52. The entorhinal cortex of the monkey: II. Cortical afferents.
    J Comp Neurol. 1987 Oct 15;264(3):356-95 PMID: 2445796
  53. Brain activity underlying encoding and retrieval of source memory.
    Cereb Cortex. 2002 Oct;12(10):1048-56 PMID: 12217968
  54. Parahippocampal projections to posterior auditory association cortex (area Tpt) in Old-World monkeys.
    Exp Brain Res. 1988;70(2):406-16 PMID: 3384041
  55. Building memories: remembering and forgetting of verbal experiences as predicted by brain activity.
    Science. 1998 Aug 21;281(5380):1188-91 PMID: 9712582
  56. Temporal lobe metabolic differences in medication-free outpatients with schizophrenia via the PET-600.
    Neuropsychopharmacology. 1996 Dec;15(6):541-54 PMID: 8946428
  57. Functional organization of the hippocampal memory system.
    Proc Natl Acad Sci U S A. 1996 Nov 26;93(24):13500-7 PMID: 8942963
  58. Requirement for hippocampal CA3 NMDA receptors in associative memory recall.
    Science. 2002 Jul 12;297(5579):211-8 PMID: 12040087
  59. A familiarity signal in human anterior medial temporal cortex?
    Hippocampus. 2003;13(2):301-4 PMID: 12699337
  60. Reduced hippocampal activation during encoding and recognition of words in schizophrenia patients.
    Am J Psychiatry. 2003 Jul;160(7):1305-12 PMID: 12832246
  61. A cortical-hippocampal system for declarative memory.
    Nat Rev Neurosci. 2000 Oct;1(1):41-50 PMID: 11252767
  62. Smaller anterior hippocampal formation volume in antipsychotic-naive patients with first-episode schizophrenia.
    Am J Psychiatry. 2003 Dec;160(12):2190-7 PMID: 14638589
  63. Hippocampal-neocortical interaction: a hierarchy of associativity.
    Hippocampus. 2000;10(4):420-30 PMID: 10985281
  64. Conjunctive representations in learning and memory: principles of cortical and hippocampal function.
    Psychol Rev. 2001 Apr;108(2):311-45 PMID: 11381832
  65. Probing the human hippocampus using rCBF: contrasts in schizophrenia.
    Hippocampus. 2001;11(5):543-50 PMID: 11732707
  66. Increased temporal lobe glucose use in chronic schizophrenic patients.
    Biol Psychiatry. 1989 Apr 1;25(7):835-51 PMID: 2785820
  67. Brain structure, genetic liability, and psychotic symptoms in subjects at high risk of developing schizophrenia.
    Biol Psychiatry. 2001 May 15;49(10):811-23 PMID: 11343678
  68. The neuropathology of schizophrenia. A critical review of the data and their interpretation.
    Brain. 1999 Apr;122 ( Pt 4):593-624 PMID: 10219775
  69. Transitive inference in schizophrenia: impairments in relational memory organization.
    Schizophr Res. 2004 Jun 1;68(2-3):235-47 PMID: 15099606
  70. Remembering or knowing: electrophysiological evidence for an episodic memory deficit in schizophrenia.
    Psychol Med. 2002 Oct;32(7):1261-71 PMID: 12420895
  71. Hippocampal dysfunction during episodic memory encoding in patients with schizophrenia-an fMRI study.
    Schizophr Res. 2003 Nov 1;64(1):83-5 PMID: 14511805
  72. Recognition memory for single items and for associations is similarly impaired following damage to the hippocampal region.
    Learn Mem. 2002 Sep-Oct;9(5):238-42 PMID: 12359833
  73. An anatomical study of converging sensory pathways within the cerebral cortex of the monkey.
    Brain. 1970;93(4):793-820 PMID: 4992433
  74. Making memories: brain activity that predicts how well visual experience will be remembered.
    Science. 1998 Aug 21;281(5380):1185-7 PMID: 9712581
  75. Dynamics of the hippocampus during encoding and retrieval of face-name pairs.
    Science. 2003 Jan 24;299(5606):577-80 PMID: 12543980
  76. Functional imaging of memory retrieval in deficit vs nondeficit schizophrenia.
    Arch Gen Psychiatry. 1999 Dec;56(12 ):1117-23 PMID: 10591289
  77. Recognition memory: what are the roles of the perirhinal cortex and hippocampus?
    Nat Rev Neurosci. 2001 Jan;2(1):51-61 PMID: 11253359
  78. Relative sparing of item recognition memory in a patient with adult-onset damage limited to the hippocampus.
    Hippocampus. 2002;12(3):325-40 PMID: 12099484
  79. Patterns of cerebral blood flow in schizophrenia.
    Br J Psychiatry. 1992 Feb;160:179-86 PMID: 1540757
  80. Regional cerebral blood flow in patients with schizophrenia: relevance to symptom structures.
    Psychiatry Res. 1996 May 31;67(1):49-58 PMID: 8797242
  81. Activation of Heschl's gyrus during auditory hallucinations.
    Neuron. 1999 Mar;22(3):615-21 PMID: 10197540
  82. Effects of extensive temporal lobe damage or mild hypoxia on recollection and familiarity.
    Nat Neurosci. 2002 Nov;5(11):1236-41 PMID: 12379865
  83. Conceptual and perceptual novelty effects in human medial temporal cortex.
    Hippocampus. 2005;15(3):326-32 PMID: 15490462
  84. Simple memory: a theory for archicortex.
    Philos Trans R Soc Lond B Biol Sci. 1971 Jul 1;262(841):23-81 PMID: 4399412
  85. Impaired hippocampal function during the detection of novel words in schizophrenia.
    Biol Psychiatry. 2004 Apr 1;55(7):668-75 PMID: 15038994
  86. Schizophrenia.
    N Engl J Med. 1994 Mar 10;330(10):681-90 PMID: 8107719
  87. Conservation of hippocampal memory function in rats and humans.
    Nature. 1996 Jan 18;379(6562):255-7 PMID: 8538790
  88. Impaired recruitment of the hippocampus during conscious recollection in schizophrenia.
    Nat Neurosci. 1998 Aug;1(4):318-23 PMID: 10195166
  89. Hippocampal volumes in schizophrenic twins.
    Arch Gen Psychiatry. 2004 Apr;61(4):346-53 PMID: 15066892
  90. Differential effects of early hippocampal pathology on episodic and semantic memory.
    Science. 1997 Jul 18;277(5324):376-80 PMID: 9219696
  91. Remembering episodes: a selective role for the hippocampus during retrieval.
    Nat Neurosci. 2000 Nov;3(11):1149-52 PMID: 11036273
  92. Backward masking performance in unaffected siblings of schizophrenic patients. Evidence for a vulnerability indicator.
    Arch Gen Psychiatry. 1997 May;54(5):465-72 PMID: 9152100
  93. Symptoms of schizophrenia. Methods, meanings, and mechanisms.
    Arch Gen Psychiatry. 1995 May;52(5):341-51 PMID: 7726714
  94. Syndromes of chronic schizophrenia.
    Br J Psychiatry. 1990 Oct;157:558-61 PMID: 2131138
  95. Multiple routes to memory: distinct medial temporal lobe processes build item and source memories.
    Proc Natl Acad Sci U S A. 2003 Feb 18;100(4):2157-62 PMID: 12578977
  96. Why there are complementary learning systems in the hippocampus and neocortex: insights from the successes and failures of connectionist models of learning and memory.
    Psychol Rev. 1995 Jul;102(3):419-57 PMID: 7624455
  97. Reduced temporal limbic structure volumes on magnetic resonance images in first episode schizophrenia.
    Psychiatry Res. 1990 Apr;35(1):1-13 PMID: 2367608
  98. Hippocampal morphometry in schizophrenia by high dimensional brain mapping.
    Proc Natl Acad Sci U S A. 1998 Sep 15;95(19):11406-11 PMID: 9736749
  99. Temporal lobe pathology in schizophrenia: a quantitative magnetic resonance imaging study.
    Am J Psychiatry. 1989 Apr;146(4):464-72 PMID: 2929746
  100. Confirmation of reduced temporal limbic structure volume on magnetic resonance imaging in male patients with schizophrenia.
    Psychiatry Res. 1996 Jul 31;67(2):135-43 PMID: 8876013
  101. Three cases of enduring memory impairment after bilateral damage limited to the hippocampal formation.
    J Neurosci. 1996 Aug 15;16(16):5233-55 PMID: 8756452
  102. Regional specificity of hippocampal volume reductions in first-episode schizophrenia.
    Neuroimage. 2004 Apr;21(4):1563-75 PMID: 15050580
  103. Some connections of the entorhinal (area 28) and perirhinal (area 35) cortices of the rhesus monkey. II. Frontal lobe afferents.
    Brain Res. 1975 Sep 12;95(1):25-38 PMID: 1156867
  104. Ionotropic glutamate receptors and expression of N-methyl-D-aspartate receptor subunits in subregions of human hippocampus: effects of schizophrenia.
    Am J Psychiatry. 2000 Jul;157(7):1141-9 PMID: 10873924
  105. Hippocampal CA3 NMDA receptors are crucial for memory acquisition of one-time experience.
    Neuron. 2003 Apr 24;38(2):305-15 PMID: 12718863
  106. Memory strength and repetition suppression: multimodal imaging of medial temporal cortical contributions to recognition.
    Neuron. 2005 Sep 1;47(5):751-61 PMID: 16129403
  107. The hippocampus in schizophrenia: a review of the neuropathological evidence and its pathophysiological implications.
    Psychopharmacology (Berl). 2004 Jun;174(1):151-62 PMID: 15205886
  108. Functional magnetic resonance imaging (fMRI) activity in the hippocampal region during recognition memory.
    J Neurosci. 2000 Oct 15;20(20):7776-81 PMID: 11027241
Article Info
Journal
Current neurology and neuroscience reports
Abbr.
Curr Neurol Neurosci Rep
ISSN
1528-4042
DOI
10.1007/s11910-005-0067-3
Published
2005-07-00
Pages
249-56
Language
English
Region
United States
NLM ID
100931790
Subset
IM
External Links
PubMed source DOI: 10.1007/s11910-005-0067-3 View journal details
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: [email protected]

Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2