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PMID: 16013541 Published · ppublish English Clinical Trial Journal Article Randomized Controlled Trial Research Support, Non-U.S. Gov't

Effect of postoperative analgesic protocol on limb function following onychectomy in cats.

Journal of the American Veterinary Medical Association ·Vol. 227 ·No. 1 ·2005-07-01 ·Pages 89-93

Romans CW, Gordon WJ, Robinson DA, Evans R, Conzemius MG

Abstract

To evaluate the analgesic effects of topical administration of bupivacaine, i.m. administration of butorphanol, and transdermal administration of fentanyl in cats undergoing onychectomy. Prospective study. 27 healthy adult cats. Cats were randomly assigned to 1 of 3 treatment groups, and unilateral (left forefoot) onychectomy was performed. Gait analysis was performed before and 1, 2, 3, and 12 days after surgery. All forces were expressed as a percentage of the cat's body weight. On day 2, peak vertical force (PVF) was significantly decreased in cats treated with bupivacaine, compared with cats treated with butorphanol or fentanyl. The ratio of left forelimb PVF to PVF of the other 3 limbs was significantly lower on day 2 in cats treated with bupivacaine than in cats treated with fentanyl. No significant differences in vertical impulse (VI) were found between groups on any day. Values for PVF, VI, and the PVF ratio increased progressively following surgery. However, for all 3 groups, values were still significantly decreased, compared with baseline values, 12 days after surgery. Results suggest that limb function following onychectomy is significantly better in cats treated with fentanyl transdermally or butorphanol i.m. than in cats treated with bupivacaine topically. Regardless of the analgesic regimen, limb function was still significantly reduced 12 days after surgery, suggesting that long-term analgesic treatment should be considered for cats undergoing onychectomy. Irrigation of the surgical incisions with bupivacaine prior to wound closure cannot be recommended as the sole method for providing postoperative analgesia in cats undergoing onychectomy.

MeSH Terms
Administration, Topical Analgesia/methods,veterinary Analgesics, Opioid/therapeutic use Anesthetics, Local/therapeutic use Animals Bupivacaine/therapeutic use Butorphanol/therapeutic use Cats/physiology,surgery Fentanyl/therapeutic use Forelimb/physiology,surgery Gait/drug effects,physiology Hoof and Claw/physiology,surgery Injections, Intramuscular/veterinary Postoperative Care/methods,veterinary Prospective Studies Random Allocation Time Factors Treatment Outcome
Chemicals
Analgesics, Opioid Anesthetics, Local Butorphanol Fentanyl Bupivacaine
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Romans Cory W
Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA.
Gordon Wanda J
Robinson Duane A
Evans Richard
Conzemius Michael G
Article Info
Journal
Journal of the American Veterinary Medical Association
Abbr.
J Am Vet Med Assoc
ISSN
0003-1488
Published
2005-07-01
Pages
89-93
Language
English
Region
United States
NLM ID
7503067
Subset
IM
Corrections
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