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LiteratureArticle Details
PMID: 16048967
Published · ppublish
English
Journal Article
Research Support, Non-U.S. Gov't
First detection of a carbapenem-hydrolyzing metalloenzyme in two enterobacteriaceae isolates in Spain.
Abstract
Two strains of Enterobacteriaceae, Escherichia coli and Klebsiella pneumoniae, producing VIM-1 were isolated for the first time in Spain. In both strains, bla(VIM-1) was found to be carried on a gene cassette inserted into a class 1 integron. The bla(VIM-1)-containing integron was located on a transferable plasmid.
MeSH 主题词
Anti-Bacterial Agents/pharmacology
Carbapenems/metabolism,pharmacology
Conjugation, Genetic
Enterobacteriaceae Infections/microbiology
Escherichia coli/drug effects,enzymology,genetics,isolation & purification
Humans
Integrons/genetics
Klebsiella pneumoniae/drug effects,enzymology,genetics,isolation & purification
Microbial Sensitivity Tests
Molecular Sequence Data
Plasmids/genetics
Sequence Analysis, DNA
Spain
beta-Lactam Resistance
beta-Lactamases/genetics,metabolism
化学物质
Anti-Bacterial Agents
Carbapenems
VIM-1 metallo-beta-lactamase
beta-Lactamases
Article Info
Journal
Antimicrobial agents and chemotherapy
Abbr.
Antimicrob Agents Chemother
ISSN
0066-4804
Published
2005-08-00
页码
3492-4
Language
English
Country/Region
United States
NLM ID
0315061
数据资源
GENBANK
AY970968,
AY987853
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