Home LiteratureArticle Details
PMID: 16117633 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Review

The Air noncoding RNA: an imprinted cis-silencing transcript.

Cold Spring Harbor symposia on quantitative biology ·Vol. 69 ·2004-00-00 ·Pages 55-66

Braidotti G, Baubec T, Pauler F, Seidl C, Smrzka O, Stricker S, Yotova I, Barlow DP

Abstract

暂无摘要

MeSH Terms
Animals Aurora Kinases Dosage Compensation, Genetic Epigenesis, Genetic Female Genetic Complementation Test Genomic Imprinting Humans Male Mice Multigene Family Protein Serine-Threonine Kinases/genetics RNA, Messenger/genetics,metabolism RNA, Untranslated/genetics Receptor, IGF Type 2/genetics Silencer Elements, Transcriptional Transcription, Genetic
Chemicals
RNA, Messenger RNA, Untranslated Receptor, IGF Type 2 Aurora Kinases Protein Serine-Threonine Kinases
Authors & Affiliations
8 authors, click to expand affiliations / ORCID
Braidotti G
AFI, Swinburne University of Technology, Hawthorn, Victoria 3122, Australia.
Baubec T
Pauler F
Seidl C
Smrzka O
Stricker S
Yotova I
Barlow D P
References (72)
72 references, click to expand
  1. Parental imprinting of an Igf-2 transgene.
    Mol Reprod Dev. 1993 Aug;35(4):382-90 PMID: 8398116
  2. The insulin-like growth factor type-2 receptor gene is imprinted in the mouse but not in humans.
    Nat Genet. 1993 Sep;5(1):74-8 PMID: 8220428
  3. Dynamics of DNA methylation during development.
    Bioessays. 1993 Nov;15(11):709-13 PMID: 8292001
  4. Allele-specific gene expression in mammals: the curious case of the imprinted RNAs.
    Genes Dev. 1994 Aug 15;8(16):1867-74 PMID: 7525406
  5. Regulation of embryonic growth and lysosomal targeting by the imprinted Igf2/Mpr gene.
    Nature. 1994 Dec 1;372(6505):464-7 PMID: 7984240
  6. Biallelic expression of imprinted genes in the mouse germ line: implications for erasure, establishment, and mechanisms of genomic imprinting.
    Genes Dev. 1995 Aug 1;9(15):1857-68 PMID: 7649473
  7. Conservation of a maternal-specific methylation signal at the human IGF2R locus.
    Hum Mol Genet. 1995 Oct;4(10):1945-52 PMID: 8595419
  8. Allele-specific expression and total expression levels of imprinted genes during early mouse development: implications for imprinting mechanisms.
    Genes Dev. 1995 Dec 15;9(24):3097-108 PMID: 8543154
  9. Deletion of the H19 differentially methylated domain results in loss of imprinted expression of H19 and Igf2.
    Genes Dev. 1998 Dec 1;12(23):3693-702 PMID: 9851976
  10. Lack of reciprocal genomic imprinting of sense and antisense RNA of mouse insulin-like growth factor II receptor in the central nervous system.
    Biochem Biophys Res Commun. 1999 Apr 13;257(2):604-8 PMID: 10198258
  11. Loss of imprinting of a paternally expressed transcript, with antisense orientation to KVLQT1, occurs frequently in Beckwith-Wiedemann syndrome and is independent of insulin-like growth factor II imprinting.
    Proc Natl Acad Sci U S A. 1999 Apr 27;96(9):5203-8 PMID: 10220444
  12. Imprinting and X-chromosome inactivation.
    Results Probl Cell Differ. 1999;25:73-90 PMID: 10339742
  13. Origin of gene overlap: the case of TCP1 and ACAT2.
    Genetics. 1999 Jun;152(2):743-54 PMID: 10353914
  14. Enhancer competition between H19 and Igf2 does not mediate their imprinting.
    Proc Natl Acad Sci U S A. 1999 Aug 17;96(17):9733-8 PMID: 10449763
  15. Aberrant imprinting of the insulin-like growth factor II receptor gene in Wilms' tumor.
    Oncogene. 1997 Mar 6;14(9):1041-6 PMID: 9070652
  16. Paternal repression of the imprinted mouse Igf2r locus occurs during implantation and is stable in all tissues of the post-implantation mouse embryo.
    Mech Dev. 1997 Jan;61(1-2):141-9 PMID: 9076684
  17. Characterization of the C3 YAC contig from proximal mouse chromosome 17 and analysis of allelic expression of genes flanking the imprinted Igf2r gene.
    Genomics. 1997 Aug 1;43(3):285-97 PMID: 9268631
  18. Biallelic transcription of Igf2 and H19 in individual cells suggests a post-transcriptional contribution to genomic imprinting.
    Curr Biol. 1999 Oct 21;9(20):1199-202 PMID: 10531031
  19. An imprinted transcript, antisense to Nesp, adds complexity to the cluster of imprinted genes at the mouse Gnas locus.
    Proc Natl Acad Sci U S A. 2000 Mar 28;97(7):3342-6 PMID: 10716699
  20. Mit1/Lb9 and Copg2, new members of mouse imprinted genes closely linked to Peg1/Mest(1).
    FEBS Lett. 2000 Apr 28;472(2-3):230-4 PMID: 10788617
  21. The imprinted antisense RNA at the Igf2r locus overlaps but does not imprint Mas1.
    Nat Genet. 2000 May;25(1):19-21 PMID: 10802648
  22. Methylation of a CTCF-dependent boundary controls imprinted expression of the Igf2 gene.
    Nature. 2000 May 25;405(6785):482-5 PMID: 10839546
  23. CTCF mediates methylation-sensitive enhancer-blocking activity at the H19/Igf2 locus.
    Nature. 2000 May 25;405(6785):486-9 PMID: 10839547
  24. Sequence conservation and variability of imprinting in the Beckwith-Wiedemann syndrome gene cluster in human and mouse.
    Hum Mol Genet. 2000 Jul 22;9(12):1829-41 PMID: 10915772
  25. Delta-like and gtl2 are reciprocally expressed, differentially methylated linked imprinted genes on mouse chromosome 12.
    Curr Biol. 2000 Sep 21;10(18):1135-8 PMID: 10996796
  26. Disruption of imprinted X inactivation by parent-of-origin effects at Tsix.
    Cell. 2000 Sep 29;103(1):17-27 PMID: 11051544
  27. Chromosome elimination in sciarid flies.
    Bioessays. 2001 Mar;23(3):242-50 PMID: 11223881
  28. Genomic imprinting: parental influence on the genome.
    Nat Rev Genet. 2001 Jan;2(1):21-32 PMID: 11253064
  29. X-chromosome inactivation: counting, choice and initiation.
    Nat Rev Genet. 2001 Jan;2(1):59-67 PMID: 11253071
  30. Regulation of imprinted X-chromosome inactivation in mice by Tsix.
    Development. 2001 Apr;128(8):1275-86 PMID: 11262229
  31. Non-imprinted Igf2r expression decreases growth and rescues the Tme mutation in mice.
    Development. 2001 May;128(10):1881-7 PMID: 11311167
  32. Allelic IGF2R repression does not correlate with expression of antisense RNA in human extraembryonic tissues.
    Genomics. 2001 May 1;73(3):331-7 PMID: 11350125
  33. Impaired activity of the extraneuronal monoamine transporter system known as uptake-2 in Orct3/Slc22a3-deficient mice.
    Mol Cell Biol. 2001 Jul;21(13):4188-96 PMID: 11390648
  34. Investigation of elements sufficient to imprint the mouse Air promoter.
    Mol Cell Biol. 2001 Aug;21(15):5008-17 PMID: 11438657
  35. Divergent evolution in M6P/IGF2R imprinting from the Jurassic to the Quaternary.
    Hum Mol Genet. 2001 Aug 15;10(17):1721-8 PMID: 11532981
  36. Bidirectional action of the Igf2r imprint control element on upstream and downstream imprinted genes.
    Genes Dev. 2001 Sep 15;15(18):2361-6 PMID: 11562346
  37. The IC-SNURF-SNRPN transcript serves as a host for multiple small nucleolar RNA species and as an antisense RNA for UBE3A.
    Hum Mol Genet. 2001 Nov 1;10(23):2687-700 PMID: 11726556
  38. Chromosomal silencing and localization are mediated by different domains of Xist RNA.
    Nat Genet. 2002 Feb;30(2):167-74 PMID: 11780141
  39. The non-coding Air RNA is required for silencing autosomal imprinted genes.
    Nature. 2002 Feb 14;415(6873):810-3 PMID: 11845212
  40. Integrating mRNA processing with transcription.
    Cell. 2002 Feb 22;108(4):501-12 PMID: 11909521
  41. Genomic imprinting during seed development.
    Adv Genet. 2002;46:165-214 PMID: 11931224
  42. Imprinted genes have few and small introns.
    Nat Genet. 1996 Mar;12(3):234-7 PMID: 8589711
  43. XIST RNA paints the inactive X chromosome at interphase: evidence for a novel RNA involved in nuclear/chromosome structure.
    J Cell Biol. 1996 Feb;132(3):259-75 PMID: 8636206
  44. Mouse mutants lacking the type 2 IGF receptor (IGF2R) are rescued from perinatal lethality in Igf2 and Igf1r null backgrounds.
    Dev Biol. 1996 Aug 1;177(2):517-35 PMID: 8806828
  45. Maternal-specific methylation of the human IGF2R gene is not accompanied by allele-specific transcription.
    Genomics. 1996 Jan 15;31(2):158-66 PMID: 8824797
  46. Mammals that break the rules: genetics of marsupials and monotremes.
    Annu Rev Genet. 1996;30:233-60 PMID: 8982455
  47. Stabilization of Xist RNA mediates initiation of X chromosome inactivation.
    Cell. 1997 Oct 3;91(1):99-107 PMID: 9335338
  48. Imprinted expression of the Igf2r gene depends on an intronic CpG island.
    Nature. 1997 Oct 16;389(6652):745-9 PMID: 9338788
  49. Igf2 imprinting does not require its own DNA methylation or H19 RNA.
    Genes Dev. 1998 Jul 15;12(14):2200-7 PMID: 9679064
  50. Antisense RNA in imprinting: spreading silence through Air.
    Trends Genet. 2002 Sep;18(9):434-7 PMID: 12175797
  51. Chromatin modification and epigenetic reprogramming in mammalian development.
    Nat Rev Genet. 2002 Sep;3(9):662-73 PMID: 12209141
  52. Allele-specific histone lysine methylation marks regulatory regions at imprinted mouse genes.
    EMBO J. 2002 Dec 2;21(23):6560-70 PMID: 12456662
  53. Visualizing RNA molecules inside the nucleus of living cells.
    Methods. 2003 Jan;29(1):51-7 PMID: 12543071
  54. A differentially methylated region within the gene Kcnq1 functions as an imprinted promoter and silencer.
    Hum Mol Genet. 2003 Feb 1;12(3):283-94 PMID: 12554682
  55. Molecular links between X-inactivation and autosomal imprinting: X-inactivation as a driving force for the evolution of imprinting?
    Curr Biol. 2003 Mar 18;13(6):R242-54 PMID: 12646153
  56. Asynchronous replication timing of imprinted loci is independent of DNA methylation, but consistent with differential subnuclear localization.
    Genes Dev. 2003 Mar 15;17(6):759-73 PMID: 12651894
  57. RNAs templating chromatin structure for dosage compensation in animals.
    Bioessays. 2003 May;25(5):434-42 PMID: 12717814
  58. Imprinted facultative heterochromatization in mealybugs.
    Genetica. 2003 Mar;117(2-3):271-9 PMID: 12723706
  59. What good is genomic imprinting: the function of parent-specific gene expression.
    Nat Rev Genet. 2003 May;4(5):359-68 PMID: 12728278
  60. RNA-FISH to analyze allele-specific expression.
    Methods Mol Biol. 2001;181:169-80 PMID: 12843449
  61. Imprinted silencing of Slc22a2 and Slc22a3 does not need transcriptional overlap between Igf2r and Air.
    EMBO J. 2003 Jul 15;22(14):3696-704 PMID: 12853484
  62. Quantification of expression and methylation of the Igf2r imprinted gene in segmental trisomic mouse model.
    Genomics. 2003 Sep;82(3):261-8 PMID: 12906851
  63. Asymmetric regulation of imprinting on the maternal and paternal chromosomes at the Dlk1-Gtl2 imprinted cluster on mouse chromosome 12.
    Nat Genet. 2003 Sep;35(1):97-102 PMID: 12937418
  64. An ICE pattern crystallizes.
    Nat Genet. 2003 Sep;35(1):11-2 PMID: 12947402
  65. Deficiency in the organic cation transporters 1 and 2 (Oct1/Oct2 [Slc22a1/Slc22a2]) in mice abolishes renal secretion of organic cations.
    Mol Cell Biol. 2003 Nov;23(21):7902-8 PMID: 14560032
  66. Genomic imprinting: intricacies of epigenetic regulation in clusters.
    Annu Rev Cell Dev Biol. 2003;19:237-59 PMID: 14570570
  67. The histone code regulating expression of the imprinted mouse Igf2r gene.
    Endocrinology. 2003 Dec;144(12):5658-70 PMID: 12975326
  68. FREP: a database of functional repeats in mouse cDNAs.
    Nucleic Acids Res. 2004 Jan 1;32(Database issue):D471-5 PMID: 14681460
  69. Genomic imprinting in mammalian development: a parental tug-of-war.
    Trends Genet. 1991 Feb;7(2):45-9 PMID: 2035190
  70. Maternal-specific methylation of the imprinted mouse Igf2r locus identifies the expressed locus as carrying the imprinting signal.
    Cell. 1993 Apr 9;73(1):61-71 PMID: 8462104
  71. Parental genomic imprinting of the human IGF2 gene.
    Nat Genet. 1993 May;4(1):98-101 PMID: 8099843
  72. Allele-specific replication timing of imprinted gene regions.
    Nature. 1993 Jul 29;364(6436):459-63 PMID: 8332218
Article Info
Journal
Cold Spring Harbor symposia on quantitative biology
Abbr.
Cold Spring Harb Symp Quant Biol
ISSN
0091-7451
Published
2004-00-00
Pages
55-66
Language
English
Region
United States
NLM ID
1256107
PMCID
PMC2847179
Subset
IM
Grants
Austrian Science Fund FWF · F 1718 · Austria
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: [email protected]