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PMID: 16131520 Published · ppublish English Journal Article Research Support, N.I.H., Extramural Research Support, U.S. Gov't, P.H.S.

HAPLOT: a graphical comparison of haplotype blocks, tagSNP sets and SNP variation for multiple populations.

Bioinformatics (Oxford, England) ·Vol. 21 ·No. 20 ·2005-10-15 ·Pages 3938-9

Gu S, Pakstis AJ, Kidd KK

Abstract

Understanding of human variation relevant to association studies can benefit from population comparison, especially comparing populations in the same geographical region. Variations in linkage disequilibrium patterns, in tagSNP sets, and in SNP heterozygosities among populations can be used to infer the evolutionary pattern. We present here a win32 system based Perl/Tk application for visual comparisons of these variations in different populations. The application package is available at http://info.med.yale.edu/genetics/kkidd/programs.html [email protected].

MeSH Terms
Chromosome Mapping/methods Computer Graphics DNA Mutational Analysis/methods Expressed Sequence Tags Genetic Variation/genetics Haplotypes/genetics Polymorphism, Single Nucleotide/genetics Software User-Computer Interface
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Gu Sheng
Department of Genetics, Yale University School of Medicine, New Haven, USA. [email protected]
Pakstis Andrew J
Kidd Kenneth K
Article Info
Journal
Bioinformatics (Oxford, England)
Abbr.
Bioinformatics
ISSN
1367-4803
Published
2005-10-15
Epub
2005-00-30
Pages
3938-9
Language
English
Region
England
NLM ID
9808944
Subset
IM
Grants
NIGMS NIH HHS · GM57672 · United States
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