This work investigates the use of computational fluid dynamics (CFD) to model air flow and particle transport associated with an inhaling anatomical mannequin. The studied condition is typically representative of occupational velocities (Re = 1920) and at-rest breathing (R = U(o)/U(m) = 0.11). Methods to verify and validate CFD simulations are detailed to demonstrate convergence and describe the model's uncertainties. The standard k-epsilon model provided a reasonable flow field, although vertical velocity components were consistently smaller than the experimental validation data, owing to truncation of the computational model at hip height. Laminar particle trajectory studies indicated that the modeled velocity field resulted in a shift of particle aspiration fractions toward particles smaller than those determined experimentally, consistent with the vertical velocity field differences.
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