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PMID: 16174871 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Review

A strategy for integrative computational physiology.

Physiology (Bethesda, Md.) ·Vol. 20 ·2005-10-00 ·Pages 316-25

Hunter P, Nielsen P

Abstract

Organ function (the heart beat for example) can only be understood through knowledge of molecular and cellular processes within the constraints of structure-function relations at the tissue level. A quantitative modeling framework that can deal with these multiscale issues is described here under the banner of the International Union of Physiological Sciences Physiome Project.

MeSH Terms
Cell Physiological Phenomena Computational Biology/methods Databases, Factual Humans Models, Biological Models, Cardiovascular Physiology/methods User-Computer Interface
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Hunter Peter
Bioengineering Institute, University of Auckland, Auckland, New Zealand. [email protected]
Nielsen Poul
Article Info
Journal
Physiology (Bethesda, Md.)
Abbr.
Physiology (Bethesda)
ISSN
1548-9213
DOI
10.1152/physiol.00022.2005
Email
[email protected]
Published
2005-10-00
Pages
316-25
Language
English
Region
United States
NLM ID
101208185
Subset
IM
Grants
Wellcome Trust · United Kingdom
External Links
PubMed source DOI: 10.1152/physiol.00022.2005 View journal details
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