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PMID: 16287991 Published · ppublish English Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Review

Role of acid/base transporters in the male reproductive tract and potential consequences of their malfunction.

Physiology (Bethesda, Md.) ·Vol. 20 ·2005-12-00 ·Pages 417-28

Pastor-Soler N, Piétrement C, Breton S

Abstract

Acid/base transporters play a key role in establishing an acidic luminal environment for sperm maturation and storage in the male reproductive tract. Impairment of the acidification capacity of the epididymis, via either genetic mutations or exposure to environmental factors, may have profound consequences on male fertility.

MeSH Terms

Acid-Base Equilibrium Acids/metabolism Animals Genitalia, Male/metabolism Humans Infertility, Male/etiology Male Membrane Transport Proteins/physiology

Chemicals

Acids Membrane Transport Proteins

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Pastor-Soler Nuria

Program in Membrane Biology/Nephrology Division, Massachusetts General Hospital and Harvard Medical School, Boston, USA.

Piétrement Christine

Breton Sylvie

Article Info

Journal

Physiology (Bethesda, Md.)

Abbr.

Physiology (Bethesda)

ISSN

1548-9213

DOI

10.1152/physiol.00036.2005

Published

2005-12-00

Pages

417-28

Language

English

Region

United States

NLM ID

101208185

Subset

Grants

NICHD NIH HHS · HD-40793 · United States

NIDDK NIH HHS · DK-38452 · United States

NICHD NIH HHS · R01 HD040793 · United States

NIDDK NIH HHS · P01 DK038452 · United States

NICHD NIH HHS · K08-HD-45524 · United States

External Links

PubMed source DOI: 10.1152/physiol.00036.2005 View journal details

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Role of acid/base transporters in the male reproductive tract and potential consequences of their malfunction.

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