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PMID: 16289799 Published · ppublish English Controlled Clinical Trial Journal Article

Anxiety and depression associated with migraine: influence on migraine subjects' disability and quality of life, and acute migraine management.

Pain ·Vol. 118 ·No. 3 ·2005-12-05 ·Pages 319-326

Lantéri-Minet M, Radat F, Chautard MH, Lucas C

Abstract

Anxiety and depression are reported to be frequently associated with migraine but how they impact on migraine-related disability, migraine subjects' quality of life, and medical and therapeutic management of migraine attacks has not been investigated. FRAMIG 3 is a nation-wide population-based postal survey carried out in France according to the 2004 international classification of headache disorders. Subjects who had had migraine attacks during the last 3 months (subjects with 'active migraine', N = 1957) were analysed for migraine-related disability (MIDAS score), quality of life (SF-12 questionnaire), and anxiety and depression (Hospital Anxiety and Depression Scale [HADS]) in comparison with non-migraine subjects (N = 8287). Survey results indicate that 50.6% of subjects with active migraine were anxious and/or depressive (28.0% had anxiety alone, 3.5% depression alone, and 19.1% both anxiety and depression; P < or = 0.01 versus non-migraine subjects for anxiety alone and combined anxiety and depression, NS for depression alone). Although, migraine-associated anxiety and depression do not appear to influence the drugs taken by migraine subjects for the acute treatment of migraine attacks, perceived treatment efficacy and satisfaction with treatment are lower in subjects with anxiety alone or combined with depression than in subjects with neither anxiety nor depression. Anxiety and depression should be systemically looked for and cared for in subjects consulting for migraine.

MeSH Terms
Adult Anxiety/epidemiology,prevention & control,psychology Comorbidity Depression/epidemiology,prevention & control,psychology Disability Evaluation Employment/statistics & numerical data Female France/epidemiology Health Surveys Humans Male Middle Aged Migraine Disorders/epidemiology,psychology,therapy Prevalence Quality of Life Risk Assessment/methods Risk Factors Sick Leave/statistics & numerical data Statistics as Topic
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Lantéri-Minet Michel
Department of Evaluation and Treatment of Pain, University Teaching Hospital, Hospital Pasteur, 06602 Nice, France Department of Treatment of Chronic Pain Patients, Pellegrin University Teaching Hospital, 33000 Bordeaux, France AstraZeneca France, Rueil-Malmaison, France Neurological Clinic, Hospital Salengro, Lille, France.
Radat Françoise
Chautard Marie-Hélène
Lucas Christian
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Article Info
Journal
Pain
Abbr.
Pain
ISSN
0304-3959
DOI
10.1016/j.pain.2005.09.010
Published
2005-12-05
Epub
2005-00-14
Pages
319-326
Language
English
Region
United States
NLM ID
7508686
Subset
IM
External Links
PubMed source DOI: 10.1016/j.pain.2005.09.010 View journal details
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