Solvent Production and Morphological Changes in Clostridium acetobutylicum.

Applied and environmental microbiology ·Vol. 43 ·No. 6 ·1982-06-00 ·Pages 1434-9

Jones DT, van der Westhuizen A, Long S, Allcock ER, Reid SJ, Woods DR

Abstract

The morphological and cytological changes which occurred in Clostridium acetobutylicum P262 during the production of acetone, butanol, and ethanol in an industrial fermentation medium were identified and correlated with the growth and physiological changes. The swollen, cigar-shaped clostridial forms were involved in the conversion of acids to neutral solvents, and there was a correlation between the number of clostridial forms and the production of solvents. Sporulation mutants which were unable to form clostridial stages (cls mutants) did not produce solvents. Oligosporogenous mutants which showed reduced clostridial stage formation produced intermediate levels of solvents. Sporulation mutants blocked after the clostridial stage, which were unable to form mature spores (spo mutants), produced normal levels of solvents.

Authors & Affiliations

6 authors, click to expand affiliations / ORCID

Jones D T

Department of Microbiology, University of Cape Town, Rondebosch 7700, South Africa.

van der Westhuizen A

Long S

Allcock E R

Reid S J

Woods D R

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13 references, click to expand

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Article Info

Journal

Applied and environmental microbiology

Abbr.

Appl Environ Microbiol

ISSN

0099-2240

DOI

10.1128/aem.43.6.1434-1439.1982

Published

1982-06-00

Pages

1434-9

Language

English

Region

United States

NLM ID

7605801

PMCID

PMC244251

External Links

PubMed source DOI: 10.1128/aem.43.6.1434-1439.1982 PMC Full Text View journal details

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Solvent Production and Morphological Changes in Clostridium acetobutylicum.

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