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PMID: 16381901 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

The LIFEdb database in 2006.

Nucleic acids research ·Vol. 34 ·No. Database issue ·2006-01-01 ·Pages D415-8

Mehrle A, Rosenfelder H, Schupp I, del Val C, Arlt D, Hahne F, Bechtel S, Simpson J, Hofmann O, Hide W, Glatting KH, Huber W, Pepperkok R, Poustka A, Wiemann S

Abstract

LIFEdb (http://www.LIFEdb.de) integrates data from large-scale functional genomics assays and manual cDNA annotation with bioinformatics gene expression and protein analysis. New features of LIFEdb include (i) an updated user interface with enhanced query capabilities, (ii) a configurable output table and the option to download search results in XML, (iii) the integration of data from cell-based screening assays addressing the influence of protein-overexpression on cell proliferation and (iv) the display of the relative expression ('Electronic Northern') of the genes under investigation using curated gene expression ontology information. LIFEdb enables researchers to systematically select and characterize genes and proteins of interest, and presents data and information via its user-friendly web-based interface.

MeSH Terms
Cell Proliferation Computational Biology DNA, Complementary/chemistry Databases, Genetic Gene Expression Genes Genomics Internet Proteins/analysis,genetics,metabolism Recombinant Fusion Proteins/metabolism Systems Integration User-Computer Interface
Chemicals
DNA, Complementary Proteins Recombinant Fusion Proteins
Authors & Affiliations
15 authors, click to expand affiliations / ORCID
Mehrle Alexander
Division Molecular Genome Analysis, German Cancer Research Center, Im Neuenheimer Feld 580, D-69120 Heidelberg, Germany. [email protected]
Rosenfelder Heiko
Schupp Ingo
del Val Coral
Arlt Dorit
Hahne Florian
Bechtel Stephanie
Simpson Jeremy
Hofmann Oliver
Hide Winston
Glatting Karl-Heinz
Huber Wolfgang
Pepperkok Rainer
Poustka Annemarie
Wiemann Stefan
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12 references, click to expand
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Article Info
Journal
Nucleic acids research
Abbr.
Nucleic Acids Res
ISSN
1362-4962
DOI
10.1093/nar/gkj139
Email
[email protected]
Published
2006-01-01
Pages
D415-8
Language
English
Region
England
NLM ID
0411011
PMCID
PMC1347501
Subset
IM
External Links
PubMed source DOI: 10.1093/nar/gkj139 PMC Full Text View journal details
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