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PMID: 16496022 Published · ppublish English Journal Article Review

The model organism as a system: integrating 'omics' data sets.

Nature reviews. Molecular cell biology ·Vol. 7 ·No. 3 ·2006-03-00 ·Pages 198-210

Joyce AR, Palsson BØ

Abstract

Various technologies can be used to produce genome-scale, or 'omics', data sets that provide systems-level measurements for virtually all types of cellular components in a model organism. These data yield unprecedented views of the cellular inner workings. However, this abundance of information also presents many hurdles, the main one being the extraction of discernable biological meaning from multiple omics data sets. Nevertheless, researchers are rising to the challenge by using omics data integration to address fundamental biological questions that would increase our understanding of systems as a whole.

MeSH Terms
Animals Cell Physiological Phenomena DNA/genetics,metabolism Genome Genomics Models, Biological Neural Networks, Computer Proteins/genetics,metabolism Proteome Transcription, Genetic
Chemicals
Proteins Proteome DNA
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Joyce Andrew R
Bioinformatics Program, University of California, San Diego, 9500 Gilman Drive, La Jolla, California 92093-0412, USA. [email protected]
Palsson Bernhard Ø
Article Info
Journal
Nature reviews. Molecular cell biology
Abbr.
Nat Rev Mol Cell Biol
ISSN
1471-0072
Published
2006-03-00
Pages
198-210
Language
English
Region
England
NLM ID
100962782
Subset
IM
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