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PMID: 16499989 Published · ppublish English Journal Article Review

How did Saccharomyces evolve to become a good brewer?

Trends in genetics : TIG ·Vol. 22 ·No. 4 ·2006-04-00 ·Pages 183-6

Piskur J, Rozpedowska E, Polakova S, Merico A, Compagno C

Abstract

Brewing and wine production are among the oldest technologies and their products are almost indispensable in our lives. The central biological agents of beer and wine fermentation are yeasts belonging to the genus Saccharomyces, which can accumulate ethanol. Recent advances in comparative genomics and bioinformatics have made it possible to elucidate when and why yeasts produce ethanol in high concentrations, and how this remarkable trait originated and developed during their evolutionary history. Two research groups have shed light on the origin of the genes encoding alcohol dehydrogenase and the process of ethanol accumulation in Saccharomyces cerevisiae.

MeSH Terms
Alcohol Dehydrogenase/genetics,metabolism Ethanol/metabolism Gene Expression Regulation, Fungal Saccharomyces cerevisiae/genetics,metabolism Saccharomyces cerevisiae Proteins/genetics,metabolism Transcription, Genetic
Chemicals
Saccharomyces cerevisiae Proteins Ethanol ADH2 protein, S cerevisiae Alcohol Dehydrogenase
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Piskur Jure
Cell and Organism Biology, Lund University, Sölvegatan 35, 22362 Lund, Sweden. [email protected]
Rozpedowska Elzbieta
Polakova Silvia
Merico Annamaria
Compagno Concetta
Article Info
Journal
Trends in genetics : TIG
Abbr.
Trends Genet
ISSN
0168-9525
Published
2006-04-00
Epub
2006-00-24
Pages
183-6
Language
English
Region
England
NLM ID
8507085
Subset
IM
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