Genomic comparison of Mycobacterium avium subsp. paratuberculosis sheep and cattle strains by microarray hybridization.
Microarray-based comparisons of three Mycobacterium avium subsp. paratuberculosis isolates, including one sheep strain and two cattle strains, identified three large genomic deletions in the sheep strain, totaling 29,208 bp and involving 24 open reading frames. These deletions may help explain some of the differences in pathogenicity and host specificity observed between the cattle and sheep strains of Mycobacterium avium subsp. paratuberculosis.
11 references, click to expand
-
Molecular epidemiology of Mycobacterium avium subsp. paratuberculosis: IS900 restriction fragment length polymorphism and IS1311 polymorphism analyses of isolates from animals and a human in Australia.J Clin Microbiol. 2000 Sep;38(9):3240-8 PMID: 10970365
-
Mycobacterium avium subsp. paratuberculosis strains from cattle and sheep can be distinguished by a PCR test based on a novel DNA sequence difference.J Clin Microbiol. 2002 Dec;40(12):4760-2 PMID: 12454189
-
Characterization of genetic differences between Mycobacterium avium subsp. paratuberculosis type I and type II isolates.J Clin Microbiol. 2003 Nov;41(11):5215-23 PMID: 14605167
-
Extensive genomic polymorphism within Mycobacterium avium.J Bacteriol. 2004 Sep;186(18):6332-4 PMID: 15342607
-
Identification of two groups of Mycobacterium paratuberculosis strains by restriction endonuclease analysis and DNA hybridization.J Clin Microbiol. 1990 Jul;28(7):1591-6 PMID: 2166089
-
Deletion of an mmpL gene and multiple associated genes from the genome of the S strain of Mycobacterium avium subsp. paratuberculosis identified by representational difference analysis and in silico analysis.Mol Cell Probes. 2005 Dec;19(6):371-84 PMID: 16226868
-
Polymorphisms in IS1311, an insertion sequence common to Mycobacterium avium and M. avium subsp. paratuberculosis, can be used to distinguish between and within these species.Mol Cell Probes. 1998 Dec;12(6):349-58 PMID: 9843652
-
Comparative genomic hybridizations reveal genetic regions within the Mycobacterium avium complex that are divergent from Mycobacterium avium subsp. paratuberculosis isolates.J Bacteriol. 2005 Apr;187(7):2406-15 PMID: 15774884
-
Genomic polymorphisms for Mycobacterium avium subsp. paratuberculosis diagnostics.J Clin Microbiol. 2005 Aug;43(8):3704-12 PMID: 16081899
-
The complete genome sequence of Mycobacterium avium subspecies paratuberculosis.Proc Natl Acad Sci U S A. 2005 Aug 30;102(35):12344-9 PMID: 16116077
-
Characterization by restriction endonuclease analysis and DNA hybridization using IS900 of bovine, ovine, caprine and human dependent strains of Mycobacterium paratuberculosis isolated in various localities.Vet Microbiol. 1995 Aug;45(4):311-8 PMID: 7483244
Contact
No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong
Qilu Normal University · Genelibs Bioinformatics Lab
750 Shunhua Rd, Jinan
2F, Bldg F, University Science Park
Tel: 0531-88819269
WeChat Official Account
Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.
Business Email
E-mail: [email protected]
Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2
