Fluorescent-antibody marker for vaccine-induced rubella antibodies.
Tests with LLC-MK2 and BHK-21 cells showed that the fluorescent-antibody (FA) procedure can be used to differentiate antibodies resulting from natural infection and antibodies stimulated by rubella vaccine virus. Negative or weak FA reactions in LLC-MK2 cells and strong reactions in BHK-21 cells indicated antibody stimulated by the vaccine virus; strong reactions in both cell systems reflected naturally acquired immunity.
6 references, click to expand
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Consequences of natural exposure to rubella during pregnancy.Proc Soc Exp Biol Med. 1968 Jan;127(1):340-4 PMID: 4171308
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Specific response of the immunoglobulins to rubella infection.Proc Soc Exp Biol Med. 1968 May;128(1):206-10 PMID: 4172931
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Attenuated rubella vaccination in families: observations on the lack of fluorescent antibody response and on the use of blood collected on filter paper discs in the hemagglutination-inhibition test.J Lab Clin Med. 1969 Jul;74(1):98-102 PMID: 4892624
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Complement-fixing and fluorescent antibody responses to an attenuated Rubella virus vaccine.Am J Epidemiol. 1970 Apr;91(4):351-4 PMID: 4912184
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Rubella hemagglutinin prepared with alkaline extraction of virus grown in suspension culture of BHK-21 cells.Proc Soc Exp Biol Med. 1967 May;125(1):162-7 PMID: 6027517
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RUBELLA ANTIBODIES IN HUMAN SERUM: DETECTION BY THE INDIRECT FLUORESCENT ANTIBODY TECHNIC.Science. 1964 Aug 28;145(3635):943-5 PMID: 14163822
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