Feedback regulation of arginine biosynthesis in blue-green algae and photosynthetic bacteria.

Hoare, D. S. (The University of Texas, Austin), and S. L. Hoare. Feedback regulation of arginine biosynthesis in blue-green algae and photosynthetic bacteria. J. Bacteriol. 92:375-379. 1966.-A number of blue-green algae and photosynthetic bacteria synthesize arginine from glutamate via acetylated intermediates. Cell-free extracts of these photosynthetic microorganisms contain an N-acetyl glutamate phosphokinase, which is specifically inhibited by arginine. They also contain a transacetylase which forms ornithine from alphaN-acetyl ornithine and glutamate. The transacetylase appears to be specific for l-glutamate. Arginine synthesis and its regulation by feedback inhibition in photosynthetic microorganisms differ from that in Escherichia coli and other Enterobacteriaceae.