Are viroids escaped introns?

Proceedings of the National Academy of Sciences of the United States of America ·Vol. 78 ·No. 8 ·1981-08-00 ·Pages 5014-5

Diener TO

Abstract

A complex of considerable stability is possible between the 5' end of U1 RNA and a specific nucleotide sequence of the potato spindle tuber viroid complement. Because base-pairing between the 5' end of U1 RNA and the ends of introns is believed by some to be responsible for the precise alignment and correct excision of introns, the U1-related sequence may represent the two ends of a presumed intron ancestor of the viroid complement after circularization.

Authors & Affiliations

1 authors, click to expand affiliations / ORCID

Diener T O

Plant Virology Laboratory, Plant Protection Institute, Agricultural Research, Science and Education Administration, U.S. Department of Agriculture, Beltsville, Maryland 20705.

References (16)

16 references, click to expand

Molecular cloning and characterization of potato spindle tuber viroid cDNA sequences.
Proc Natl Acad Sci U S A. 1980 Sep;77(9):5302-6 PMID: 16592877
Hybridization of potato spindle tuber viroid to cellular DNA of normal plants.
Proc Natl Acad Sci U S A. 1976 Jul;73(7):2453-7 PMID: 16592335
RNA sequences complementary to citrus exocortis viroid in nucleic acid preparations from infected Gynura aurantiaca.
Proc Natl Acad Sci U S A. 1978 Feb;75(2):896-900 PMID: 16592500
Viroids: a class of subviral pathogens.
Angew Chem Int Ed Engl. 1980;19(4):231-43 PMID: 6155812
Correlation between splicing sites within an intron and their sequence complementarity with U1 RNA.
Cell. 1980 Oct;21(3):689-96 PMID: 6159982
A mechanism for RNA splicing.
Proc Natl Acad Sci U S A. 1980 Apr;77(4):1877-9 PMID: 6246511
One gene's intron is another gene's exon.
Nature. 1981 Feb 5;289(5797):439-40 PMID: 7007884
A pathway of cytochrome b mRNA processing in yeast mitochondria: specific splicing steps and an intron-derived circular DNA.
Cell. 1980 Feb;19(2):321-9 PMID: 6986990
Are snRNPs involved in splicing?
Nature. 1980 Jan 10;283(5743):220-4 PMID: 7350545
Split genes and RNA splicing.
Science. 1979 Apr 20;204(4390):264-71 PMID: 373120
Mechanism for RNA splicing of gene transcripts.
FEBS Lett. 1979 Oct 1;106(1):5-7 PMID: 499501
Viroids: structure and function.
Science. 1979 Aug 31;205(4409):859-66 PMID: 472709
Nucleotide sequence and secondary structure of potato spindle tuber viroid.
Nature. 1978 May 18;273(5659):203-8 PMID: 643081
Improved estimation of secondary structure in ribonucleic acids.
Nat New Biol. 1973 Nov 14;246(150):40-1 PMID: 4519026
Primary sequence of U-1 nuclear ribonucleic acid of Novikoff hepatoma ascites cells.
J Biol Chem. 1974 Oct 25;249(20):6486-94 PMID: 4370679
Potato spindle tuber viroid. XII. An investigation of viroid RNA as a messenger for protein synthesis.
Virology. 1974 Sep;61(1):281-6 PMID: 4606921

Article Info

Journal

Proceedings of the National Academy of Sciences of the United States of America

Abbr.

Proc Natl Acad Sci U S A

ISSN

0027-8424

DOI

10.1073/pnas.78.8.5014

Published

1981-08-00

Pages

5014-5

Language

English

Region

United States

NLM ID

7505876

PMCID

PMC320322

External Links

PubMed source DOI: 10.1073/pnas.78.8.5014 PMC Full Text View journal details

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