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PMID: 16593888 Published · ppublish English Journal Article

Repressor of P elements in Drosophila melanogaster: Cytotype determination by a defective P element carrying only open reading frames 0 through 2.

Proceedings of the National Academy of Sciences of the United States of America ·Vol. 84 ·No. 21 ·1987-11-00 ·Pages 7605-8

Nitasaka E, Mukai T, Yamazaki T

Abstract

The P element is a type of transposable element in Drosophila melanogaster. Characteristics of the syndrome of "hybrid dysgenesis" are due to transposition of P elements, and the molecular mechanism for regulation of this transposition has been unknown. In this study a Q strain (which carries only defective P elements in its genome but still is able to repress the transposition of complete P elements although defective in transposase activity) was used to determine the structure of the P element with this repressor (or P cytotype-determining) domain. Examination of the cytotype and structure of the P elements of particular strains with reduced copy number of P elements showed that the P element with a repressor domain was defective, being deleted between bases 1991 and 2448. This region corresponds to most of the third intron [between open reading frame (ORF) 2 and ORF 3] as well as half the ORF 3 of an intact P element. Therefore ORF 3 was deemed to be unnecessary for repressor production.

Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Nitasaka E
Laboratory of Population Genetics, Department of Biology, Kyushu University, Fukuoka 812, Japan.
Mukai T
Yamazaki T
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Article Info
Journal
Proceedings of the National Academy of Sciences of the United States of America
Abbr.
Proc Natl Acad Sci U S A
ISSN
0027-8424
DOI
10.1073/pnas.84.21.7605
Published
1987-11-00
Pages
7605-8
Language
English
Region
United States
NLM ID
7505876
PMCID
PMC299348
External Links
PubMed source DOI: 10.1073/pnas.84.21.7605 PMC Full Text View journal details
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