Home LiteratureArticle Details
PMID: 16649942 Published · ppublish English Journal Article

Cholecystoenterostomy for treatment of extrahepatic biliary tract obstruction in cats: 22 cases (1994-2003).

Journal of the American Veterinary Medical Association ·Vol. 228 ·No. 9 ·2006-05-01 ·页码 1376-82

Buote NJ, Mitchell SL, Penninck D, Freeman LM, Webster CR

Abstract

To identify factors associated with outcome in cats with extrahepatic biliary tract obstruction (EHBTO) that undergo biliary diversion surgery. Retrospective case series. 22 cats. Medical records of cats with surgically confirmed EHBTO that underwent cholecystoenterostomy were reviewed. Clinical signs and physical examination findings included vomiting, anorexia, icterus, lethargy, weakness, and weight loss. Common clinicopathologic abnormalities included high serum hepatic enzyme activities and serum bilirubin concentration. Abdominal ultrasonography was performed in 21 cats, and all 21 had findings consistent with EHBTO. Eleven of 15 cats in which blood pressure was monitored had intraoperative hypotension. Eighteen cats had anemia following surgery, and 14 cats had persistent hypotension. Extrahepatic biliary tract obstruction was a result of neoplasia in 9 cats and chronic inflammatory disease in 13. Fourteen cats survived long enough to be discharged from the hospital, but only 6 survived > 6 months after surgery, all of which had chronic inflammatory disease. Median survival time for cats with neoplasia (14 days) was significantly shorter than that for cats with inflammatory disease (255 days). No other variable was associated with outcome. Results suggest that cats with EHBTO secondary to neoplasia have a poorer prognosis than cats with EHBTO secondary to chronic inflammatory disease. However, the overall prognosis for cats with EHBTO undergoing cholecystoenterostomy must be considered guarded to poor, and the incidence of perioperative complications is high.

MeSH 主题词
Animals Cat Diseases/etiology,pathology,surgery Cats Cholecystectomy/methods,veterinary Cholestasis, Extrahepatic/etiology,pathology,surgery,veterinary Female Hyperbilirubinemia/etiology,veterinary Hypotension/etiology,veterinary Inflammation/complications,veterinary Liver/enzymology Male Neoplasms/complications,veterinary Postoperative Complications/veterinary Retrospective Studies Survival Analysis Treatment Outcome Vomiting/etiology,veterinary Weight Loss
作者与单位
共 5 位作者,点击展开单位 / ORCID
Buote Nicole J
Department of Clinical Sciences, Cummings School of Veterinary Medicine at Tufts University, North Grafton, MA 01536, USA.
Mitchell Susan L
Penninck Dominique
Freeman Lisa M
Webster Cynthia R L
Article Info
Journal
Journal of the American Veterinary Medical Association
Abbr.
J Am Vet Med Assoc
ISSN
0003-1488
Published
2006-05-01
页码
1376-82
Language
English
Country/Region
United States
NLM ID
7503067
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: [email protected]