Urokinase-dependent proteolysis in cultured colon cancer is directed by its receptor.

Colonic Neoplasms/metabolism,pathology Extracellular Matrix/pathology Humans Laminin/metabolism Neoplasm Invasiveness Peptide Hydrolases/metabolism Plasminogen/metabolism Plasminogen Inactivators/pharmacology Receptors, Cell Surface/metabolism,physiology Receptors, Urokinase Plasminogen Activator Tumor Cells, Cultured Urokinase-Type Plasminogen Activator/metabolism

Laminin PLAUR protein, human Plasminogen Inactivators Receptors, Cell Surface Receptors, Urokinase Plasminogen Activator Plasminogen Peptide Hydrolases Urokinase-Type Plasminogen Activator