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PMID: 16680922 Published · ppublish English Journal Article

Questionnaire evaluation and risk factor identification for nonallergic vasomotor rhinitis.

Brandt D, Bernstein JA

Abstract

Chronic rhinitis, a prevalent primary care disorder associated with significant comorbidities, is often incorrectly diagnosed. As a result, inappropriate treatment leads to higher health care costs and poor clinical outcomes. To verify whether responses to specific questions may help in the diagnosis of nonallergic vasomotor rhinitis (NAVMR). A questionnaire listing allergic and nonallergic triggers was blindly distributed to 100 random new patients with chronic rhinitis in an allergist's office. Questionnaire and physician diagnoses were compared. Allergic triggers included cat, dog, feathers, other furry animals, and symptoms during the spring, summer, and fall seasons. Nonallergic triggers included temperature changes, diesel and car exhaust, tobacco smoke, perfumes and fragrances, incense, cleaning products, newsprint, hairspray, and alcoholic beverages, spicy foods, or eating. The construct validity and internal consistency indicated that the questionnaire was a good tool for diagnosing NAVMR. Multivariate analysis revealed that the absence of outdoor symptoms in the spring (odds ratio [OR], 7.76; 95% confidence interval [CI], 1.18-51.22; P = .03), no parental history of allergy (OR, 5.16; 95% CI, 1.05-25.20; P = .04), no symptoms around cats (OR, 3.82; 95% CI, 0.59-24.83; P = .16), the presence of symptoms around perfumes and fragrances (OR, 4.875; 95% CI, 1.05-22.60; P = .04), and age at symptom onset (OR, 1.08; 95% CI, 1.02-1.14; P = .008) were predictive of NAVMR. Specific questionnaire responses may help primary care physicians accurately diagnose NAVMR. Questions asked of patients by physicians to diagnose allergic rhinitis do not correlate well with physician diagnosis.

MeSH Terms
Adult Allergens Diagnosis, Differential Factor Analysis, Statistical Female Humans Irritants Male Predictive Value of Tests Regression Analysis Rhinitis/diagnosis,etiology Risk Factors Surveys and Questionnaires
Chemicals
Allergens Irritants
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Brandt Dominique
Center for Epidemiology and Biostatistics, Cincinnati Children's Hospital Medical Center, Ohio, USA.
Bernstein Jonathan A
Article Info
Journal
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology
Abbr.
Ann Allergy Asthma Immunol
ISSN
1081-1206
Published
2006-04-00
Pages
526-32
Language
English
Region
United States
NLM ID
9503580
Subset
IM
Corrections
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