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PMID: 16704777 Published · ppublish English Journal Article

Clostridium difficile infection in patients discharged from US short-stay hospitals, 1996-2003.

Emerging infectious diseases ·Vol. 12 ·No. 3 ·2006-03-00 ·Pages 409-15

McDonald LC, Owings M, Jernigan DB

Abstract

US hospital discharges for which Clostridium difficile-associated disease (CDAD) was listed as any diagnosis doubled from 82,000 (95% confidence interval [CI] 71,000-94,000) or 31/100,000 population in 1996 to 178,000 (95% CI 151,000-205,000) or 61/100,000 in 2003; this increase was significant between 2000 and 2003 (slope of linear trend 9.48; 95% CI 6.16-12.80, p = 0.01). The overall rate during this period was severalfold higher in persons >65 years of age (228/100,000) than in the age group with the next highest rate, 45-64 years (40/100,000; p < or = 0.001). CDAD appears to be increasing rapidly in the United States and is disproportionately affecting older persons. Clinicians should be aware of the increasing risk for CDAD and make efforts to control transmission of C. difficile and prevent disease.

MeSH Terms
Adolescent Adult Aged Aging Clostridioides difficile Enterocolitis, Pseudomembranous/epidemiology,microbiology Female Hospitalization Humans Length of Stay Male Middle Aged Patient Discharge Risk Factors Time Factors United States/epidemiology
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
McDonald L Clifford
Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA. [email protected]
Owings Maria
Jernigan Daniel B
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Article Info
Journal
Emerging infectious diseases
Abbr.
Emerg Infect Dis
ISSN
1080-6040
DOI
10.3201/eid1205.051064
Email
[email protected]
Published
2006-03-00
Pages
409-15
Language
English
Region
United States
NLM ID
9508155
PMCID
PMC3291455
Subset
IM
External Links
PubMed source DOI: 10.3201/eid1205.051064 PMC Full Text View journal details
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