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PMID: 16774572 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Emergence of Proteus mirabilis carrying the bla metallo-beta-lactamase gene.

Vourli S, Tsorlini H, Katsifa H, Polemis M, Tzouvelekis LS, Kontodimou A, Vatopoulos AC

Abstract

Seven genetically related Proteus mirabilis clinical isolates from a hospital in Thessaloniki, Greece, exhibited decreased susceptibility to imipenem and carried a bla(VIM-1) metallo-beta-lactamase gene. PCR mapping revealed that bla(VIM-1) was part of a class 1 integron that was probably located in the chromosome and also included the aacA7, dhfr and aadA genes. This is the first description of the bla(VIM-1) metallo-beta-lactamase gene in P. mirabilis.

MeSH 主题词
Anti-Bacterial Agents/therapeutic use Carbapenems/therapeutic use Cross Infection/drug therapy,microbiology Humans Imipenem/therapeutic use Microbial Sensitivity Tests/methods Proteus Infections/drug therapy Proteus mirabilis/drug effects,genetics,isolation & purification beta-Lactam Resistance/genetics beta-Lactamases/genetics
化学物质
Anti-Bacterial Agents Carbapenems Imipenem VIM-1 metallo-beta-lactamase beta-Lactamases
作者与单位
共 7 位作者,点击展开单位 / ORCID
Vourli S
Department of Microbiology, National School of Public Health, Athens, Greece.
Tsorlini H
Katsifa H
Polemis M
Tzouvelekis L S
Kontodimou A
Vatopoulos A C
Article Info
Journal
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases
Abbr.
Clin Microbiol Infect
ISSN
1198-743X
Published
2006-07-00
页码
691-4
Language
English
Country/Region
England
NLM ID
9516420
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