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PMID: 16891838 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Review

Brain plasticity under cochlear implant stimulation.

Advances in oto-rhino-laryngology ·Vol. 64 ·2006-00-00 ·Pages 89-108

Kral A, Tillein J

Abstract

The benefit of cochlear implantation crucially depends on the ability of the brain to learn to classify neural activity evoked by the cochlear implant. Brain plasticity is a complex property with massive developmental changes after birth. The present paper reviews the experimental work on auditory plasticity and focuses on the plasticity required for adaptation to cochlear implant stimulation. It reviews the data on developmental sensitive periods in auditory plasticity of hearing, hearing-impaired and deaf, cochlear-implanted, animals. Based on the analysis of the above findings in animals and comparable data from humans, a cochlear implantation within the first 2 years of age is recommended.

MeSH Terms
Animals Auditory Cortex/growth & development,physiology Brain/growth & development,physiology Cochlear Implants Hearing Loss/physiopathology,therapy Humans Neuronal Plasticity/physiology Treatment Outcome
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Kral Andrej
Laboratories of Auditory Neuroscience, Institute of Neurophysiology and Pathophysiology, University of Hamburg, Hamburg, Germany.
Tillein Jochen
Article Info
Journal
Advances in oto-rhino-laryngology
Abbr.
Adv Otorhinolaryngol
ISSN
0065-3071
Published
2006-00-00
Pages
89-108
Language
English
Region
Switzerland
NLM ID
0242534
Subset
IM
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